ArticleInternational journal of clinical and experimental pathology2009
Correlation of macrophage inflammatory protein-2 expression and brain edema in rats after intracerebral hemorrhage.
Article in International journal of clinical and experimental pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Association between white blood cells and ultra-early hematoma growth in patients with spontaneous intracerebral hemorrhage.Heliyon · 2024Article
- Intracerebral hemorrhage induces monocyte-related gene expression within six hours: Global transcriptional profiling in swine ICH.Metabolic brain disease · 2019Article
- Preclinical Studies and Translational Applications of Intracerebral Hemorrhage.BioMed research international · 2017Review
- In vivo microdialysis sampling of cytokines from rat hippocampus: comparison of cannula implantation procedures.ACS chemical neuroscience · 2013Article
- Correlation of leukocytosis with early neurological deterioration following supratentorial intracerebral hemorrhage.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2012Article
- Preclinical and clinical research on inflammation after intracerebral hemorrhage.Progress in neurobiology · 2010Review
- Dynamic changes of inflammatory markers in brain after hemorrhagic stroke in humans: a postmortem study.Brain research · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain edema is one of the most frequent and serious complications of intracerebral hemorrhage (ICH), but its underlying mechanism remains largely unknown. In order to understand whether inflammatory mediators released from the blood after cerebral hemorrhage plays a role in brain edema, we investigated the dynamic change of the inflammatory mediator macrophage inflammatory protein-2 (MIP-2) in rat brain after ICH. Our results indicate that the expression of MIP-2 increases 2 hours and peaks 2 days after ICH. The expression of MIP-2 correlates with NF-kappaB activation and brain water content. These results suggest that MIP-2 expression may play an important role in the development of brain edema after ICH in rats.
Indexed as
Identifiers
18830379PMC2491385W76162634What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.