Evidence map›Paper›PMID 18830154›Full record

ArticleMolecules (Basel, Switzerland)2008

Effects of various drugs on alcohol-induced oxidative stress in the liver.

Mira Popovic, Snezana Janicijevic-Hudomal, Biljana Kaurinovic, Julijana Rasic, Svetlana Trivic

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Hypolipidaemic and antioxidant effect of Enicostemma littorale Blume.Asian Pacific journal of tropical biomedicine · 2011
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mira PopovicDepartment of Chemistry, Faculty of Sciences, Trg Dositeja Obradovica 3, 21000 Novi Sad, Serbia. popovic@ih.ns.ac.yu
Snezana Janicijevic-Hudomal
Biljana Kaurinovic
Julijana Rasic
Svetlana Trivic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major aim of this work was to investigate how alcohol-induced oxidative stress in combined chemotherapy changes the metabolic function of the liver in experimental animals. This research was conducted to establish how bromocriptine, haloperidol and azithromycin, applied to the experimental model, affected the antioxidative status of the liver. The following parameters were determined: reduced glutathione, activities of glutathione peroxidase, glutathione reductase, peroxidase, catalase, xanthine oxidase and lipid peroxidation intensity. Alanine transaminase was measured in serum. Alcohol stress (AO group) reduced glutathione and the activity of xanthine oxidase and glutathione peroxidase, but increased catalase and alanine transaminase activity. The best protective effect was achieved with the bromocriptine (AB1 group), while other groups had similar effects on the studied parameters.

Indexed as

Alanine TransaminaseAnimalsAzithromycinBromocriptineCatalaseEthanolGlutathioneGlutathione ReductaseHaloperidolLipid PeroxidationLiverMaleOxidative StressPeroxidaseRatsRats, WistarAlanine TransaminaseAzithromycinBromocriptineCatalaseEthanolGlutathioneGlutathione ReductaseHaloperidolPeroxidaseXanthine Oxidase

Identifiers

PMID18830154
PMCPMC6245383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.