Evidence map›Paper›PMID 18830055›Full record

ArticleThe Korean journal of parasitology2008

Keratitis by Acanthamoeba triangularis: report of cases and characterization of isolates.

Ying-Hua Xuan, Byung-Suk Chung, Yeon-Chul Hong, Hyun-Hee Kong, Tae-Won Hahn, Dong-Il Chung

Abstract readCase Reports
In one paragraph

Article in The Korean journal of parasitology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Orthokeratology lens-relatedThe Journal of international medical research · 2021
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Amoebicidal activity ofParasitology · 2021
    Article
  9. Pathogens (Basel, Switzerland) · 2021
    Article
  10. Article
  11. Update on Acanthamoeba phylogeny.Parasitology research · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying-Hua XuanDepartment of Parasitology, Kyungpook National University School of Medicine, Daegu 700-422, Korea.
Byung-Suk Chung
Yeon-Chul Hong
Hyun-Hee Kong
Tae-Won Hahn
Dong-Il Chung

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three Acanthamoeba isolates (KA/E9, KA/E17, and KA/E23) from patients with keratitis were identified as Acanthamoeba triangularis by analysis of their molecular characteristics, a species not previously recognized to be a corneal pathogen. Epidemiologic significance of A. triangularis as a keratopathogen in Korea has been discussed. Morphologic features of Acanthamoeba cysts were examined under a microscope with differential interference contrast (DIC) optics. Mitochondrial DNA (mtDNA) of the ocular isolates KA/E9, KA/E17, and KA/E23 were digested with restriction enzymes, and the restriction patterns were compared with those of reference strains. Complete nuclear 18S and mitochondrial (mt) 16S rDNA sequences were subjected to phylogenetic analysis and species identification. mtDNA RFLP of 3 isolates showed very similar patterns to those of SH621, the type strain of A. triangularis. 16S and 18S rDNA sequence analysis confirmed 3 isolates to be A. triangularis. 18S rDNA sequence differences of the isolates were 1.3% to 1.6% and those of 16S rDNA, 0.4% to 0.9% from A. triangularis SH621. To the best of our knowledge, this is the first report, confirmed by 18S and 16S rDNA sequence analysis, of keratitis caused by A. triangularis of which the type strain was isolated from human feces. Six isolates of A. triangularis had been reported from contaminated contact lens cases in southeastern Korea.

Indexed as

AcanthamoebaAcanthamoeba KeratitisAdolescentAdultAnimalsAntiprotozoal AgentsBiguanidesDNA, MitochondrialDNA, ProtozoanFemaleHumansMalePhylogenyPolymorphism, Restriction Fragment LengthRNA, Ribosomal, 16SRNA, Ribosomal, 18SAntiprotozoal AgentsBiguanidesDNA, MitochondrialDNA, ProtozoanpolihexanideRNA, Ribosomal, 16SRNA, Ribosomal, 18S

Identifiers

PMID18830055
PMCPMC2553330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.