ReviewBreast cancer research : BCR2008
Unlocking the power of cross-species genomic analyses: identification of evolutionarily conserved breast cancer networks and validation of preclinical models.
Review in Breast cancer research : BCR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Comparative proteomic profiling of the ovine and human PBMC inflammatory response.Scientific reports · 2024Article
- Rapid Assessment of Mitochondrial Complex I Activity and Metabolic Phenotyping of Breast Cancer Cells by NAD(p)H Cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019Article
- Article
- The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma.Molecular cancer research : MCR · 2015Article
- Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways.Breast cancer research : BCR · 2014Article
- Article
- Article
- Animal models and conserved processes.Theoretical biology & medical modelling · 2012Article
- The renal transcriptome of db/db mice identifies putative urinary biomarker proteins in patients with type 2 diabetes: a pilot study.American journal of physiology. Renal physiology · 2012Article
- Capturing the heterogeneity in systemic sclerosis with genome-wide expression profiling.Expert review of clinical immunology · 2011Review
- Noncanonical TGF-β signaling during mammary tumorigenesis.Journal of mammary gland biology and neoplasia · 2011Review
- Pathologic progression of mammary carcinomas in a C3(1)/SV40 T/t-antigen transgenic rat model of human triple-negative and Her2-positive breast cancer.Transgenic research · 2011Article
- Comparative functional genomics analysis of NNK tobacco-carcinogen induced lung adenocarcinoma development in Gprc5a-knockout mice.PloS one · 2010Article
- A Gprc5a tumor suppressor loss of expression signature is conserved, prevalent, and associated with survival in human lung adenocarcinomas.Neoplasia (New York, N.Y.) · 2010Article
- Social isolation reduces mammary development, tumor incidence, and expression of epigenetic regulators in wild-type and p53-heterozygotic mice.Cancer prevention research (Philadelphia, Pa.) · 2010Article
- Genomic analyses as a guide to target identification and preclinical testing of mouse models of breast cancer.Toxicologic pathology · 2010Review
- Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression.Breast cancer research : BCR · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The application of high-throughput genomic technologies has revealed that individual breast tumors display a variety of molecular features that require more personalized approaches to treatment. Several recent studies have demonstrated that a cross-species analytic approach provides a powerful means to filter through genetic complexity by identifying evolutionarily conserved genetic networks that are fundamental to the oncogenic process. Mouse-human tumor comparisons will provide insights into cellular origins of tumor subtypes, define interactive oncogenetic networks, identify potential novel therapeutic targets, and further validate as well as guide the selection of genetically engineered mouse models for preclinical testing.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.