Evidence map›Paper›PMID 18827982›Full record

ReviewImmunologic research2008

Progenitor migration to the thymus and T cell lineage commitment.

Arivazhagan Sambandam, J Jeremiah Bell, Benjamin A Schwarz, Valerie P Zediak, Anthony W Chi, Daniel A Zlotoff, Shanthi Lakshmi Krishnamoorthy, Jennifer M Burg, Avinash Bhandoola

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Recent Advancements in Regenerative Approaches for Thymus Rejuvenation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  2. Review
  3. Article
  4. Article
  5. Eliciting the T cell fate with Notch.Seminars in immunology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Arivazhagan SambandamDepartment of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
J Jeremiah Bell
Benjamin A Schwarz
Valerie P Zediak
Anthony W Chi
Daniel A Zlotoff
Shanthi Lakshmi Krishnamoorthy
Jennifer M Burg
Avinash Bhandoola
University of Pennsylvania · US

Funding

Immune System Development and RegulationT32AI055428 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALLMAN, DAVID M, OLIVER, PAULA MARIA · 2003 to 2025
$4.2M
NIAID NIH HHS T32 AI055428
6 · The paper itself

Abstract

T cells developing in the thymus are ultimately derived from bone marrow (BM) hematopoietic stem cells (HSCs). An understanding of the developmental steps between HSCs and T cells is important for gaining insight into cancers of the T lineage, improving T cell reconstitution after BM transplantation, and also to help ameliorate immunological defects in aging. In this article, we summarize our current understanding of the inter-related fields of early T cell development and thymic aging, and briefly discuss major unresolved questions in this field.

Indexed as

AgingAnimalsCell LineageCell MovementCytokinesHematopoietic Stem CellsHumansThymus GlandT-LymphocytesCytokines

Identifiers

PMID18827982
OpenAlexW2053458746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.