ArticleThe Plant cell2008
Proteolysis-independent downregulation of DELLA repression in Arabidopsis by the gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1.
Article in The Plant cell, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed, 175 citations in OpenAlex.
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- The Floral Bottleneck in a Changing Climate: Molecular Mechanisms, Knowledge Gaps, and Future Directions.International journal of molecular sciences · 2026Review
- Micropropagation and ex vitro acclimatization of Lonicera caerulea var. altaica: molecular identification and protocol optimization.Scientific reports · 2026Article
- Editing a gibberellin receptor gene improves yield and nitrogen fixation in soybean.Journal of integrative plant biology · 2026Article
- Modulation of JA-GA signaling and drought response by a truncated OsJAZ9 protein in rice.Plant signaling & behavior · 2025Article
- ThePlants (Basel, Switzerland) · 2025Article
- Structural insights into proteolysis-dependent and -independent suppression of the master regulator DELLA by the gibberellin receptor.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Identification and functional analysis of the CqGID1 homologs in quinoa.Plant cell reports · 2025Article
- CmFDa-mediated epigenetic regulation of flowering in chrysanthemum.Plant biotechnology journal · 2025Article
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Phosphorylation activates master growth regulator DELLA by promoting histone H2A binding at chromatin in Arabidopsis.Nature communications · 2024Article
- Bet-hedging and variability in plant development: seed germination and beyond.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Hormones and carbohydrates synergistically regulate the formation of swollen roots in a Chinese cabbage translocation line.Horticulture research · 2023Article
- Cloning and Functional Identification of Gibberellin Receptor SvGID1s Gene of Salix viminalis.Molecular biotechnology · 2023Article
- Seed dormancy loss from dry after-ripening is associated with increasing gibberellin hormone levels inFrontiers in plant science · 2023Article
- Editorial: Cooperation of gene regulatory networks and phytohormones in cell development and morphogenesis.Frontiers in plant science · 2023Article
- A key piece emerges in the noncanonical gibberellin signaling puzzle: PLANT UBX DOMAIN-CONTAINING PROTEIN1.Plant physiology · 2022Article
- GA signaling expands: The plant UBX domain-containing protein 1 is a binding partner for the GA receptor.Plant physiology · 2022Article
- Multi-Omics Approaches Unravel Specific Features of Embryo and Endosperm in Rice Seed Germination.Frontiers in plant science · 2022Article
- Gibberellin-related genes regulate dwarfing mechanism in wintersweet.Frontiers in plant science · 2022Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article presents evidence that DELLA repression of gibberellin (GA) signaling is relieved both by proteolysis-dependent and -independent pathways in Arabidopsis thaliana. DELLA proteins are negative regulators of GA responses, including seed germination, stem elongation, and fertility. GA stimulates GA responses by causing DELLA repressor degradation via the ubiquitin-proteasome pathway. DELLA degradation requires GA biosynthesis, three functionally redundant GA receptors GIBBERELLIN INSENSITIVE DWARF1 (GID1a, b, and c), and the SLEEPY1 (SLY1) F-box subunit of an SCF E3 ubiquitin ligase. The sly1 mutants accumulate more DELLA proteins but display less severe dwarf and germination phenotypes than the GA biosynthesis mutant ga1-3 or the gid1abc triple mutant. Interestingly, GID1 overexpression rescued the sly1 dwarf and infertility phenotypes without decreasing the accumulation of the DELLA protein REPRESSOR OF ga1-3. GID1 rescue of sly1 mutants was dependent on the level of GID1 protein, GA, and the presence of a functional DELLA motif. Since DELLA shows increasing interaction with GID1 with increasing GA levels, it appears that GA-bound GID1 can block DELLA repressor activity by direct protein-protein interaction with the DELLA domain. Thus, a SLY1-independent mechanism for GA signaling may function without DELLA degradation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.