ArticleProceedings. Biological sciences2009
Bayesian coalescent inference of major human mitochondrial DNA haplogroup expansions in Africa.
Article in Proceedings. Biological sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Article
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- Demographic expansion of an African opportunistic carnivore during the Neolithic revolution.Biology letters · 2020Article
- Neolithic millet farmers contributed to the permanent settlement of the Tibetan Plateau by adopting barley agriculture.National science review · 2019Article
- The Overlooked Tradition of "Personal Music" and Its Place in the Evolution of Music.Frontiers in psychology · 2019Article
- MitoIMP: A Computational Framework for Imputation of Missing Data in Low-Coverage Human Mitochondrial Genome.Bioinformatics and biology insights · 2019Article
- Interspecies evolutionary divergence in Liriodendron, evidence from the nucleotide variations of LcDHN-like gene.BMC evolutionary biology · 2018Article
- Music and the Meeting of Human Minds.Frontiers in psychology · 2018Review
- A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals.BMC evolutionary biology · 2017Article
- Ancient mitochondrial genome reveals trace of prehistoric migration in the east Pamir by pastoralists.Journal of human genetics · 2016Article
- 60,000 years of interactions between Central and Eastern Africa documented by major African mitochondrial haplogroup L2.Scientific reports · 2015Article
- Exploring population size changes using SNP frequency spectra.Nature genetics · 2015Article
- Genetic stratigraphy of key demographic events in Arabia.PloS one · 2015Article
- Revised timeline and distribution of the earliest diverged human maternal lineages in southern Africa.PloS one · 2015Article
- Microsatellite data show recent demographic expansions in sedentary but not in nomadic human populations in Africa and Eurasia.European journal of human genetics : EJHG · 2014Article
- Genetic variation and adaptation in Africa: implications for human evolution and disease.Cold Spring Harbor perspectives in biology · 2014Review
- The history of the North African mitochondrial DNA haplogroup U6 gene flow into the African, Eurasian and American continents.BMC evolutionary biology · 2014Article
- An unbiased resource of novel SNP markers provides a new chronology for the human Y chromosome and reveals a deep phylogenetic structure in Africa.Genome research · 2014Article
- Contrasting demographic histories of the neighboring bonobo and chimpanzee.Primates; journal of primatology · 2014Article
- Genetic aspects of athletic performance: the African runners phenomenon.Open access journal of sports medicine · 2014Review
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Abstract
Past population size can be estimated from modern genetic diversity using coalescent theory. Estimates of ancestral human population dynamics in sub-Saharan Africa can tell us about the timing and nature of our first steps towards colonizing the globe. Here, we combine Bayesian coalescent inference with a dataset of 224 complete human mitochondrial DNA (mtDNA) sequences to estimate effective population size through time for each of the four major African mtDNA haplogroups (L0-L3). We find evidence of three distinct demographic histories underlying the four haplogroups. Haplogroups L0 and L1 both show slow, steady exponential growth from 156 to 213kyr ago. By contrast, haplogroups L2 and L3 show evidence of substantial growth beginning 12-20 and 61-86kyr ago, respectively. These later expansions may be associated with contemporaneous environmental and/or cultural changes. The timing of the L3 expansion--8-12kyr prior to the emergence of the first non-African mtDNA lineages--together with high L3 diversity in eastern Africa, strongly supports the proposal that the human exodus from Africa and subsequent colonization of the globe was prefaced by a major expansion within Africa, perhaps driven by some form of cultural innovation.
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