ArticleJournal of the Royal Society, Interface2009
Structure and properties of strontium-doped phosphate-based glasses.
Article in Journal of the Royal Society, Interface, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 158 citations in OpenAlex.
- Structural, dielectric, and radiation shielding properties of erbium doped phosphate glasses.Scientific reports · 2026Article
- Research Progress of Bone Grafting: A Comprehensive Review.International journal of nanomedicine · 2025Review
- In vitro immunomodulatory effect of solid versus porous phosphate-based glass microspheres using macrophages.Heliyon · 2023Article
- Horizon of exosome-mediated bone tissue regeneration: The all-rounder role in biomaterial engineering.Materials today. Bio · 2022Review
- Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation.Bioengineering (Basel, Switzerland) · 2022Article
- Surface Modification of Bioresorbable Phosphate Glasses for Controlled Protein Adsorption.ACS biomaterials science & engineering · 2021Article
- Biodegradable materials for bone defect repair.Military Medical Research · 2020Review
- [Application and research status of bioactive glass in bone repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2020Review
- Impact of ZnO Addition on ErMaterials (Basel, Switzerland) · 2020Article
- Mesoporous Strontium-Doped Phosphate-Based Sol-Gel Glasses for Biomedical Applications.Frontiers in chemistry · 2020Article
- Impact of AgMaterials (Basel, Switzerland) · 2019Article
- In vitro cellular testing of strontium/calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration.Journal of tissue engineering and regenerative medicine · 2019Article
- Multiple and Promising Applications of Strontium (Sr)-Containing Bioactive Glasses in Bone Tissue Engineering.Frontiers in bioengineering and biotechnology · 2019Review
- Bioactive Glasses and Glass-Ceramics for Healthcare Applications in Bone Regeneration and Tissue Engineering.Materials (Basel, Switzerland) · 2018Review
- Bioactivity evaluation of collagen-based scaffolds containing a series of Sr-doped melt-quench derived phosphate-based glasses.Journal of materials science. Materials in medicine · 2018Article
- Sensitivity of novel silicate and borate-based glass structures onCeramics international · 2017Article
- Novel bioglasses for bone tissue repair and regeneration: Effect of glass design on sintering ability, ion release and biocompatibility.Materials & design · 2017Article
- Effect of strontium substitution on the cytocompatibility and 3-D scaffold structure for the xSrO-(10-x) MgO-60SiOJournal of materials science. Materials in medicine · 2017Article
- Effect of strontium inclusion on the bioactivity of phosphate-based glasses.Journal of materials science · 2017Article
- Bioactive and Antibacterial Glass Powders Doped with Copper by Ion-Exchange in Aqueous Solutions.Materials (Basel, Switzerland) · 2016Article
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Owing to similarity in both ionic size and polarity, strontium (Sr2+) is known to behave in a comparable way to calcium (Ca2+), and its role in bone metabolism has been well documented as both anti-resorptive and bone forming. In this study, novel quaternary strontium-doped phosphate-based glasses, containing 1, 3 and 5 mol% SrO, were synthesized and characterized. (31)P magic angle spinning (MAS) nuclear magnetic resonance results showed that, as the Sr2+ content is increased in the glasses, there is a slight increase in disproportionation of Q2 phosphorus environments into Q(1) and Q3 environments. Moreover, shortening and strengthening of the phosphorus to bridging oxygen distance occurred as obtained from FTIR. The general broadening of the spectral features with Sr2+ content is most probably due to the increased variation of the phosphate-cation bonding interactions caused by the introduction of the third cation. This increased disorder may be the cause of the increased degradation of the Sr-containing glasses relative to the Sr-free glass. As confirmed from elemental analysis, all Sr-containing glasses showed higher Na2O than expected and this also could be accounted for by the higher degradation of these glasses compared with Sr-free glasses. Measurements of surface free energy (SFE) showed that incorporation of strontium had no effect on SFE, and samples had relatively higher fractional polarity, which is not expected to promote high cell activity. From viability studies, however, the incorporation of Sr2+ showed better cellular response than Sr(2+)-free glasses, but still lower than the positive control. This unfavourable cellular response could be due to the high degradation nature of these glasses and not due to the presence of Sr2+.
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