Trial reportAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2008
Exercise, fitness, and neurocognitive function in older adults: the "selective improvement" and "cardiovascular fitness" hypotheses.
Trial report in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
90 citing papers in PubMed, 8 syntheses or guidelines pooled it, 250 citations in OpenAlex.
- Diversity in United States Dementia Prevention Trials: An Updated Systematic Review of Eligibility Criteria and Recruitment Strategies.Dementia and geriatric cognitive disorders · 2025Pooled it
- Does music support executive functions and affective responses during acute exercise? A systematic review and meta-analysis.Frontiers in psychology · 2025Pooled it
- Comparative efficacy and safety of non-pharmacological interventions as adjunctive treatment for vascular dementia: a systematic review and network meta-analysis.Frontiers in neurology · 2024Pooled it
- Effects of Exercise Training Interventions on Executive Function in Older Adults: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Systematic review and meta-analysis investigating moderators of long-term effects of exercise on cognition in healthy individuals.Nature human behaviour · 2020Pooled it
- The impact of behavioral interventions on cognitive function in healthy older adults: A systematic review.Ageing research reviews · 2019Pooled it
- Aerobic exercise to improve cognitive function in older people without known cognitive impairment.The Cochrane database of systematic reviews · 2015Pooled it
- Physical activity and cognitive function in individuals over 60 years of age: a systematic review.Clinical interventions in aging · 2014Pooled it
- Benefits of exercise in patients with rheumatoid arthritis: a randomized controlled trial of a patient-specific exercise programme.Clinical rheumatology · 2020Trial
- Physical fitness and physical activity association with cognitive function and quality of life: baseline cross-sectional analysis of the PREDIMED-Plus trial.Scientific reports · 2020Trial
- Mind-body exercise improves cognitive function and modulates the function and structure of the hippocampus and anterior cingulate cortex in patients with mild cognitive impairment.NeuroImage. Clinical · 2019Trial
- Cerebral oxygenation during cortical activation: the differential influence of three exercise training modalities. A randomized controlled trial.European journal of applied physiology · 2017Trial
- Exercise Test Performance Reveals Evidence of the Cardiorespiratory Fitness Hypothesis.Journal of aging and physical activity · 2017Trial
- Benefits of resistance exercise in lean women with fibromyalgia: involvement of IGF-1 and leptin.BMC musculoskeletal disorders · 2017Trial
- Enhancing cognitive functioning in the elderly: multicomponent vs resistance training.Clinical interventions in aging · 2013Trial
- Effect of a pulmonary rehabilitation program combined with cognitive training on exercise tolerance and cognitive functions among Tunisian male patients with chronic obstructive pulmonary disease: A randomized controlled trial.Chronic respiratory diseaseTrial
- Efficacy of Aerobic Versus Non-aerobic Exercise in Mild Cognitive Impairment: A Systematic Review and Meta-Analysis Based on RCTs.Annals of Indian Academy of Neurology · 2026Article
- Article
- Motor-Cognitive Associations in Older Adults: A Cross-Sectional Study Toward Self-Assessment Tools.Behavioral sciences (Basel, Switzerland) · 2026Article
- The mediating role of psychological resilience and loneliness between physical activity and mobile phone addiction among adolescents.Frontiers in nutrition · 2026Article
30 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundAlthough basic research has uncovered biological mechanisms by which exercise could maintain and enhance adult brain health, experimental human studies with older adults have produced equivocal results. PURPOSE: This randomized clinical trial aimed to investigate the hypotheses that (a) the effects of exercise training on the performance of neurocognitive tasks in older adults is selective, influencing mainly tasks with a substantial executive control component and (b) performance in neurocognitive tasks is related to cardiorespiratory fitness.
methodsFifty-seven older adults (65-79 years) participated in aerobic or strength-and-flexibility exercise training for 10 months. Neurocognitive tasks were selected to reflect a range from little (e.g., simple reaction time) to substantial (i.e., Stroop Word-Color conflict) executive control.
resultsPerformance in tasks requiring little executive control was unaffected by participating in aerobic exercise. Improvements in Stroop Word-Color task performance were found only for the aerobic exercise group. Changes in aerobic fitness were unrelated to changes in neurocognitive function.
conclusionsAerobic exercise in older adults can have a beneficial effect on the performance of speeded tasks that rely heavily on executive control. Improvements in aerobic fitness do not appear to be a prerequisite for this beneficial effect.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.