Evidence map›Paper›PMID 18824561›Full record

ReviewGlycobiology2009

Glycobiology on the fly: developmental and mechanistic insights from Drosophila.

Kelly G ten Hagen, Liping Zhang, E Tian, Ying Zhang

Abstract readReview
In one paragraph

Review in Glycobiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. PolypeptideMolecules (Basel, Switzerland) · 2021
    Review
  4. Article
  5. Serum N-Glycome Diversity in Teleost and Chondrostrean Fishes.Frontiers in molecular biosciences · 2021
    Article
  6. Mucin-Type O-GalNAc Glycosylation in Health and Disease.Advances in experimental medicine and biology · 2021
    Article
  7. RNAi-Mediated Silencing of Pgants Shows Core 1Frontiers in physiology · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Viruses and antiviral immunity in Drosophila.Developmental and comparative immunology · 2014
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kelly G ten HagenDevelopmental Glycobiology Unit, NIDCR, National Institutes of Health, Building 30, 30 Convent Drive, MSC 4370, Bethesda, MD 20892-4370, USA. Kelly.Tenhagen@nih.gov
Liping Zhang
E Tian
Ying Zhang

Funding

Role of O-glycosylation in Animal DevelopmentZIADE000713 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI TEN HAGEN, KELLY G · 2009 to 2025
$30.6M
Role of O-glycosylation in Animal DevelopmentZ01DE000713 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI TEN HAGEN, KELLY G · 2006 to 2008
$2.0M
Intramural NIH HHS Z01 DE000713
6 · The paper itself

Abstract

Drosophila melanogaster offers many unique advantages for deciphering the complexities of glycan biosynthesis and function. The completion of the Drosophila genome sequencing project as well as the comprehensive catalogue of existing mutations and phenotypes have lead to a prolific database where many of the genes involved in glycan synthesis, assembly, modification, and recognition have been identified and characterized. Recent biochemical and molecular studies have elucidated the structure of the glycans present in Drosophila. Powerful genetic approaches have uncovered a number of critical biological roles for glycans during development that impact on our understanding of their function during mammalian development. Here, we summarize key recent findings and provide evidence for the usefulness of this model organism in unraveling the complexities of glycobiology across many species.

Indexed as

AnimalsDrosophila melanogasterFucoseGene Expression Regulation, DevelopmentalGlycomicsGlycosphingolipidsGlycosylationModels, BiologicalPolysaccharidesSignal TransductionSpecies SpecificityFucoseGlycosphingolipidsPolysaccharides

Identifiers

PMID18824561
PMCPMC2722416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.