Evidence map›Paper›PMID 18824101›Full record

ReviewCurrent opinion in neurobiology2008

Hair cell afferent synapses.

Elisabeth Glowatzki, Lisa Grant, Paul Fuchs

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Role of Calcium Signaling in Sensorineural Hearing Loss.International journal of medical sciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Hair Cell Afferent Synapses: Function and Dysfunction.Cold Spring Harbor perspectives in medicine · 2019
    Review
  9. Article
  10. Article
  11. Sensory Hair Cells: An Introduction to Structure and Physiology.Integrative and comparative biology · 2018
    Review
  12. Article
  13. Article
  14. Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elisabeth GlowatzkiDepartment of Otolaryngology, Johns Hopkins School of Medicine, 720 Rutland Avenue, Ross 824, Baltimore, MD 21205, United States. eglowat1@jhmi.edu
Lisa Grant
Paul Fuchs
Johns Hopkins University · US

Funding

The Histology CoreP30DC005211 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI FUCHS, PAUL ALBERT · 2002 to 2016
$9.1M
AFFERENT SYNAPTIC TRANSMISSION IN THE MAMMALIAN COCHLEAR01DC006476 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI GLOWATZKI, ELISABETH · 2004 to 2022
$6.4M
EXCITABILITY, SYNAPTIC FUNCTION OF COCHLEAR HAIR CELLSR01DC000276 · NIDCD · UNIVERSITY OF COLORADO DENVER · PI FUCHS, PAUL ALBERT · 1989 to 2010
$4.2M
PREDOCTORAL FELLOWSHIP PROGRAM (DISABILITY)F31DC000276 · NIDCD · LOUISIANA STATE UNIV A&M COL BATON ROUGE · PI HOROHOV, JANICE E · 1997 to 1999
–
NIDCD NIH HHS DC000276NIDCD NIH HHS DC006476NIDCD NIH HHS F31 DC000276NIDCD NIH HHS P30 DC005211NIDCD NIH HHS R01 DC000276NIDCD NIH HHS R01 DC006476
6 · The paper itself

Abstract

This review will cover advances in the study of hair cell afferent synaptic function occurring between 2005 and 2008. During this time, capacitance measurements of vesicular fusion have continued to be refined, optical methods have added insights regarding vesicle trafficking, and paired intracellular recordings have established the transfer function of the afferent synapse at high resolution. Further, genes have been identified with forms of deafness known as auditory neuropathy, and their role in afferent signaling explored in mouse models. With these advances, our view of the hair cell afferent synapse has continued to be refined, and surprising properties have been revealed that emphasize the unique role of this structure in neural function.

Indexed as

Afferent PathwaysAnimalsCalcium ChannelsHair Cells, AuditoryHumansReceptors, GlutamateSynapsesSynaptic TransmissionSynaptic VesiclesCalcium ChannelsReceptors, Glutamate

Identifiers

PMID18824101
PMCPMC2860955
OpenAlexW2121735655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.