Evidence map›Paper›PMID 18821841›Full record

ArticleTissue engineering. Part B, Reviews2008

Stem cells for heart cell therapies.

Donghui Jing, Abhirath Parikh, John M Canty, Emmanuel S Tzanakakis

Abstract read
In one paragraph

Article in Tissue engineering. Part B, Reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Potential for Stem Cell-Based Periodontal Therapy.Journal of cellular physiology · 2016
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Donghui JingDepartment of Chemical and Biological Engineering, State University of New York at Buffalo, Buffalo, New York 14260, USA.
Abhirath Parikh
John M Canty
Emmanuel S Tzanakakis

Funding

Metabolic Adaptation and Functional Recovery of Hibernating MyocardiumR01HL061610 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 2000 to 2018
$6.0M
CHRONIC ADAPTATIONS TO MYOCARDIAL ISCHEMIAR01HL055324 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CANTY, JOHN M · 1996 to 2014
$4.2M
Scalable bioprocess for cardiomyocyte generation from human embryonic stem cellsR21HL092398 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI TZANAKAKIS, EMMANOUHL · 2008 to 2009
$452k
NHLBI NIH HHS HL092398NHLBI NIH HHS HL55324NHLBI NIH HHS HL61610NHLBI NIH HHS R01 HL055324NHLBI NIH HHS R01 HL061610NHLBI NIH HHS R21 HL092398
6 · The paper itself

Abstract

Myocardial infarction-induced heart failure is a prevailing cause of death in the United States and most developed countries. The cardiac tissue has extremely limited regenerative potential, and heart transplantation for reconstituting the function of damaged heart is severely hindered mainly due to the scarcity of donor organs. To that end, stem cells with their extensive proliferative capacity and their ability to differentiate toward functional cardiomyocytes may serve as a renewable cellular source for repairing the damaged myocardium. Here, we review recent studies regarding the cardiogenic potential of adult progenitor cells and embryonic stem cells. Although large strides have been made toward the engineering of cardiac tissues using stem cells, important issues remain to be addressed to enable the translation of such technologies to the clinical setting.

Indexed as

AdultAnimalsBone Marrow CellsBone Marrow TransplantationCell DifferentiationCell DivisionEmbryonic Stem CellsHeart DiseasesHumansMiceMuscle, SkeletalMyocardiumMyocytes, CardiacStem CellsStem Cell Transplantation

Identifiers

PMID18821841
PMCPMC2710610

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.