Evidence map›Paper›PMID 18820734›Full record

ArticleChemistry of materials : a publication of the American Chemical Society

Preparation and Characterization of Porous Gold and its Application as a Platform for Immobilization of Acetylcholine Esterase.

Olga V Shulga, Kenise Jefferson, Abdul R Khan, Valerian T D'Souza, Jingyue Liu, Alexei V Demchenko, Keith J Stine

Open access · greenAbstract read
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 104 citations in OpenAlex.

  1. Article
  2. Nanoporous Gold for Enzyme Immobilization.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Self-catalytic growth of one-dimensional materials within dislocations in gold.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Square-wave voltammetry assays for glycoproteins on nanoporous gold.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2014
    Article
  10. Article
  11. Article
  12. Lectin-carbohydrate interactions on nanoporous gold monoliths.New journal of chemistry = Nouveau journal de chimie · 2013
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Olga V ShulgaDepartment of Chemistry and Biochemistry, University of Missouri - St. Louis, St. Louis, Missouri, 63121.
Kenise Jefferson
Abdul R Khan
Valerian T D'Souza
Jingyue Liu
Alexei V Demchenko
Keith J Stine
University of Missouri–St. Louis · US

Funding

STICS: Surface-Tethered Iterative Carbohydrate SynthesisR21GM072693 · NIGMS · UNIVERSITY OF MISSOURI-ST. LOUIS · PI STINE, KEITH J. · 2006 to 2007
$394k
NIGMS NIH HHS R21 GM072693
6 · The paper itself

Abstract

We report a method for fabrication of free-standing porous gold material with high surface area, and well-defined, tunable pore morphology. Porous gold is formed via a simple procedure which involves an acidic treatment of a commercially available complex white-gold alloy. We used SEM and AFM techniques to characterize the surface morphology, size and shape of the meso-pores as well as the surface roughness of the prepared porous gold samples. Formation of self-assembled monolayers of a flavin sulfide on the gold surface was used to estimate the total surface area of porous gold material. The monolayers were found to be electrochemically active by cyclic and square-wave voltammetry. It was found that 24 hour HNO(3) treatment gave a 12,400 times surface enlargement and resulted in a surface area of 14.2 m(2)/g, whereas 72 hour HNO(3) treatment resulted in a 6900 times surface enlargement and a surface area of 8.7 m(2)/g. In addition, the enzyme acetylcholine esterase was immobilized on the different porous gold surfaces in order to demonstrate biocompatibility of the porous gold material. Kinetic parameters and the amount of the immobilized acetylcholine esterase were determined.

Identifiers

PMID18820734
PMCPMC2553220
OpenAlexW2062300942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.