Evidence map›Paper›PMID 18820356›Full record

ArticleThe Indian journal of medical research2008

Investigation of a hepatitis A outbreak in children in an urban slum in Vellore, Tamil Nadu, using geographic information systems.

Thuppal V Sowmyanarayanan, Ashis Mukhopadhya, B P Gladstone, Rajiv Sarkar, Gagandeep Kang

Abstract read
In one paragraph

Article in The Indian journal of medical research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Hepatitis A Outbreak with the Concurrence ofThe American journal of tropical medicine and hygiene · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Investigating a community-wide outbreak of hepatitis a in India.Journal of global infectious diseases · 2014
    Article
  12. Article
  13. Article
  14. Hepatitis A outbreak in Ba subdivision, Fiji, October-December 2013.Western Pacific surveillance and response journal : WPSAR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thuppal V SowmyanarayananDepartments of Gastrointestinal Sciences , Christian Medical College Vellore, Tamil Nadu, India.
Ashis Mukhopadhya
B P Gladstone
Rajiv Sarkar
Gagandeep Kang

Funding

Multi-disciplinary research training in enteric infectionsD43TW007392 · FIC · CHRISTIAN MEDICAL COLLEGE · PI KANG, GAGANDEEP · 2005 to 2020
$2.9M
FIC NIH HHS D43 TW007392Wellcome TrustWellcome Trust 063144
6 · The paper itself

Abstract

BACKGROUND &

objectiveAn outbreak of symptomatic viral hepatitis in children less than 10 yr of age in Vellore, south India, was investigated and the disease pattern studied using serological and epidemiological methods, supplemented by geographic information systems (GIS) mapping.

methodsThree cases of hepatitis A were identified during routine surveillance in a birth cohort House-to-house visits were undertaken to identify other symptomatic cases and samples collected for anti- HAV IgM, ELISA testing. All cases and controls were mapped and geo-referenced using Arc View GIS 3.3. Spatial clustering was investigated using SaTScan 7.0.1 software. Drinking water sources were tested for coliform counts with the most probable number technique.

resultsOf the 965 children surveyed, 26 (2.78%) had jaundice between February to July 2006. From the 26 patients, 11 (42.3%) blood samples were obtained and tested for anti-HAV IgM; 10 (90.9%) were found to be positive. Water analysis showed high coliform counts in all samples. No spatial clustering of cases could be detected. INTERPRETATION &

conclusionThe outbreak was identified because of the symptomatic presentation of the cases. Our study highlighted the increasing detection of symptomatic children with hepatitis A virus infection. Water sources in the area were contaminated and may have served as the source of infection. The lack of clustering in GIS analysis could be due to the common water source.

Indexed as

Poverty AreasChildChild, PreschoolDisease OutbreaksFemaleHepatitis AHumansIndiaMaleUrban PopulationWater Supply

Identifiers

PMID18820356
PMCPMC3855648

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.