ArticleProceedings of the National Academy of Sciences of the United States of America1991
Mapping of human microtubule-associated protein 1B in proximity to the spinal muscular atrophy locus at 5q13.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- A human skeletal muscle stem/myotube model reveals multiple signaling targets of cancer secretome in skeletal muscle.iScience · 2023Article
- Article
- Unusual molecular findings in autosomal recessive spinal muscular atrophy.Journal of medical genetics · 1996Article
- Natural resistance to infection with Legionella pneumophila: chromosomal localization of the Lgn1 susceptibility gene.Mammalian genome : official journal of the International Mammalian Genome Society · 1995Article
- Refinement of the spinal muscular atrophy locus by genetic and physical mapping.American journal of human genetics · 1995Article
- Association between Ag1-CA alleles and severity of autosomal recessive proximal spinal muscular atrophy.American journal of human genetics · 1994Article
- Mapping of two new markers within the smallest interval harboring the spinal muscular atrophy locus by family and radiation hybrid analysis.Human genetics · 1994Article
- Use of genetic and physical mapping to locate the spinal muscular atrophy locus between two new highly polymorphic DNA markers.American journal of human genetics · 1994Article
- Linkage mapping of the spinal muscular atrophy gene.Human genetics · 1994Article
- Molecular and statistical approaches to the detection and correction of errors in genotype databases.American journal of human genetics · 1993Article
- Two novel microsatellite markers for prenatal prediction of spinal muscular atrophy (SMA).Human genetics · 1993Article
- Construction of a yeast artificial chromosome contig spanning the spinal muscular atrophy disease gene region.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Rapid diagnosis of infantile spinal muscular atrophy by direct amplification of amniocyte and CVS DNA.Journal of medical genetics · 1993Article
- Genetic linkage analysis of Canadian spinal muscular atrophy kindreds using flanking microsatellite 5q13 polymorphisms.Human genetics · 1993Article
- Mouse chromosome 13.Mammalian genome : official journal of the International Mammalian Genome Society · 1992Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
A polyclonal antiserum directed against the C-terminal domain of dystrophin was used to isolate a cDNA clone encoding an antigenically cross-reactive protein, microtubule-associated protein 1B (MAP-1B). Physical mapping of the human MAP-1B locus places its chromosomal location at 5q13, in proximity to the spinal muscular atrophy (SMA) locus. SMA is a degenerative disorder primarily affecting motor neurons. Genetic linkage analysis of SMA families using a human dinucleotide repeat polymorphism just 3' of the MAP-1B gene has shown tight linkage to SMA mutations. These mapping data together with the postulated role of MAP-1B in neuronal morphogenesis and its localization in anterior horn motor neurons suggest a possible association with SMA.
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