Evidence map›Paper›PMID 18817773›Full record

ArticleFEBS letters2008

D-Glucose sensing by a plasma membrane regulator of G signaling protein, AtRGS1.

Jeffrey C Grigston, Daniel Osuna, Wolf-Rüdiger Scheible, Chenggang Liu, Mark Stitt, Alan M Jones

Open access · bronzeAbstract read
In one paragraph

Article in FEBS letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 104 citations in OpenAlex.

  1. Review
  2. Sugar-sensing swodkoreceptors and swodkocrine signaling.Animal models and experimental medicine · 2025
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  18. Glucose signaling, AtRGS1 and plant autophagy.Plant signaling & behavior · 2019
    Review
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jeffrey C GrigstonDepartment of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA.
Daniel Osuna
Wolf-Rüdiger Scheible
Chenggang Liu
Mark Stitt
Alan M Jones
Max Planck Institute of Molecular Plant Physiology · DEUniversity of North Carolina at Chapel Hill · US

Funding

Novel Mechanisms Regulating the Heterotrimeric G Protein ComplexR01GM065989 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONES, ALAN M. · 2002 to 2023
$5.5M
NIGMS NIH HHS R01 GM065989
6 · The paper itself

Abstract

Plants use sugars as signaling molecules and possess mechanisms to detect and respond to changes in sugar availability, ranging from the level of secondary signaling molecules to altered gene transcription. G-protein-coupled pathways are involved in sugar signaling in plants. The Arabidopsis thaliana regulator of G-protein signaling protein 1 (AtRGS1) combines a receptor-like seven transmembrane domain with an RGS domain, interacts with the Arabidopsis Galpha subunit (AtGPA1) in a d-glucose-regulated manner, and stimulates AtGPA1 GTPase activity. We determined that AtRGS1 interacts with additional components, genetically defined here, to serve as a plasma membrane sensor for d-glucose. This interaction between AtRGS1 and AtGPA1 involves, in part, the seven-transmembrane domain of AtRGS1.

Indexed as

ArabidopsisArabidopsis ProteinsCell MembraneGene Expression Regulation, PlantGlucoseGTP-Binding Protein alpha SubunitsMembrane ProteinsProtein Structure, TertiaryRGS ProteinsSignal TransductionTranscription, GeneticArabidopsis ProteinsGlucoseGPA1 protein, ArabidopsisGTP-Binding Protein alpha SubunitsMembrane ProteinsRGS1 protein, ArabidopsisRGS ProteinsTHF1 protein, Arabidopsis

Identifiers

PMID18817773
PMCPMC2764299
OpenAlexW2048423082

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.