Evidence map›Paper›PMID 18817506›Full record

ReviewAnnual review of pathology2009

MicroRNAs in cancer.

Yong Sun Lee, Anindya Dutta

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annual review of pathology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 886 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
886citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

886 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  6. The Role of MicroRNA in Migraine: A Systemic Literature Review.Cellular and molecular neurobiology · 2023
    Pooled it
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826 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yong Sun LeeDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA. ad8q@virginia.edu
Anindya Dutta

Funding

MicroRNAs in differentiation of muscleR01AR053948 · NIAMS · UNIVERSITY OF VIRGINIA · PI DUTTA, ANINDYA · 2007 to 2011
$1.7M
NIAMS NIH HHS AR 053948NIAMS NIH HHS R01 AR053948
6 · The paper itself

Abstract

Within the past few years, studies on microRNA (miRNA) and cancer have burst onto the scene. Profiling of the miRNome (global miRNA expression levels) has become prevalent, and abundant miRNome data are currently available for various cancers. The pattern of miRNA expression can be correlated with cancer type, stage, and other clinical variables, so miRNA profiling can be used as a tool for cancer diagnosis and prognosis. miRNA expression analyses also suggest oncogenic (or tumor-suppressive) roles of miRNAs. miRNAs play roles in almost all aspects of cancer biology, such as proliferation, apoptosis, invasion/metastasis, and angiogenesis. Given that many miRNAs are deregulated in cancers but have not yet been further studied, it is expected that more miRNAs will emerge as players in the etiology and progression of cancer. Here we also discuss miRNAs as a tool for cancer therapy.

Indexed as

Gene Expression Regulation, NeoplasticAnimalsBiomarkers, TumorGenetic TherapyGenotypeHumansMicroRNAsNeoplasmsPhenotypePrognosisTranscription, GeneticBiomarkers, TumorMicroRNAs

Identifiers

PMID18817506
PMCPMC2769253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.