Evidence map›Paper›PMID 18815843›Full record

Trial reportJournal of general internal medicine2008

A randomized controlled trial of team-based care: impact of physician-pharmacist collaboration on uncontrolled hypertension.

Jacquelyn S Hunt, Joseph Siemienczuk, Ginger Pape, Yelena Rozenfeld, John MacKay, Benjamin H LeBlanc, Daniel Touchette

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of general internal medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 69 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 20 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02919033 naunknown statusnot on this mapstarted 2016, after this paper: background citation

A Coordinated PCP-Cardiologist Telemedicine Model (PCTM) in China's Community Hypertension Care: Study Protocol for a Randomized Controlled Trial

TypeinterventionalSponsorXu LeiRan2016 to 2018Enrolled330ConditionsHypertensionArmsUsual care, Self-management, PCTM intervention
NCT03872856 nacompletednot on this mapstarted 2019, after this paper: background citation

Home Blood Pressure Monitoring Intervention for Self-Management of High Blood Pressure Among Alaska Native People

TypeinterventionalSponsorSouthcentral FoundationRan2019 to 2023Enrolled164ConditionsHypertensionArmsBP-ICAN
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 20 syntheses or guidelines pooled it.

  1. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
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  7. Impact of integrating pharmacists into primary care teams on health systems indicators: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2019
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  9. Pharmacist services for non-hospitalised patients.The Cochrane database of systematic reviews · 2018
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  10. Patient and public perspectives of community pharmacies in the United Kingdom: A systematic review.Health expectations : an international journal of public participation in health care and health policy · 2018
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jacquelyn S HuntProvidence Physician Division, Beaverton, OR, USA.jacquelyn.hunt@providence.org
Joseph Siemienczuk
Ginger Pape
Yelena Rozenfeld
John MacKay
Benjamin H LeBlanc
Daniel Touchette

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate the effectiveness of collaborative management of hypertension by primary care-pharmacist teams in community-based clinics. STUDY

designA 12-month prospective, single-blind, randomized, controlled trial in the Providence Primary Care Research Network of patients with hypertension and uncontrolled blood pressure.

methodsAs compared to usual primary care, intervention consisted of pharmacy practitioners participating in the active management of hypertension in the primary care office according to established collaborative treatment protocols. At baseline, there was no significant difference in blood pressure between groups. Primary outcome measures were the differences in mean systolic and diastolic blood pressures between arms at study end. Secondary measures included blood pressure goal attainment (<140/90 mmHg), hypertension-related knowledge, medication adherence, home blood pressure monitoring, resource utilization, quality of life, and satisfaction.

resultsA total of 463 subjects were enrolled (n = 233 control, n = 230 intervention). Subjects receiving the intervention achieved significantly lower systolic (p = 0.007) and diastolic (p = 0.002) blood pressures compared to control (137/75 mmHg vs. 143/78 mmHg). In addition, 62% of intervention subjects achieved target blood pressure compared to 44% of control subjects (p = 0.003). The intervention group received more total office visits (7.2 vs. 4.9, p < 0.0001), however had fewer physician visits (3.2 vs. 4.7, p < 0.0001) compared to control. Intervention subjects were prescribed more antihypertensive medications (2.7 vs. 2.4, p = 0.02), but did not take more antihypertensive pills per day (2.4 vs. 2.5, p = 0.87). There were minimal differences between groups in hypertension-related knowledge, medication adherence, quality of life, or satisfaction.

conclusionsPatients randomized to collaborative primary care-pharmacist hypertension management achieved significantly better blood pressure control compared to usual care with no difference in quality of life or satisfaction.

Indexed as

Cooperative BehaviorPatient Care TeamPharmacistsPhysiciansAgedAged, 80 and overDisease ManagementFemaleHumansHypertensionMaleMiddle AgedPatient SatisfactionProspective StudiesSingle-Blind Method

Identifiers

PMID18815843
PMCPMC2596500

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.