ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2009
Alternaria infectoria brain abscess in a child with chronic granulomatous disease.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Consecutive non-Aspergillus Fungal Invasive Infections in Chronic Granulomatous Disease: Data from the French National Reference Center for Primary ImmunoDeficiencies and literature review.Journal of clinical immunology · 2025Review
- Production Systems and Age Influence Fecal Mycobiota Diversity and Composition in Swine.Microbial ecology · 2025Article
- Early Interaction of Alternaria infectoria Conidia with Macrophages.Mycopathologia · 2019Article
- Successful Posaconazole Therapy of Disseminated Alternariosis due to Alternaria infectoria in a Heart Transplant Recipient.Mycopathologia · 2017Article
- Chronic Leptomeningitis and Spinal Intradural Mass Secondary toCase reports in infectious diseases · 2016Article
- Activation of Melanin Synthesis in Alternaria infectoria by Antifungal Drugs.Antimicrobial agents and chemotherapy · 2015Article
- Black Molds and Melanized Yeasts Pathogenic to Humans.Cold Spring Harbor perspectives in medicine · 2014Review
- Modulation of Alternaria infectoria cell wall chitin and glucan synthesis by cell wall synthase inhibitors.Antimicrobial agents and chemotherapy · 2014Article
- Characterization of Alternaria infectoria extracellular vesicles.Medical mycology · 2014Article
- Fungal meningoencephalitis caused by Alternaria: a clinical case.Clinical drug investigation · 2013Article
- Chronic granulomatous disease: a review of the infectious and inflammatory complications.Clinical and molecular allergy : CMA · 2011Article
- Melanized fungi in human disease.Clinical microbiology reviews · 2010Review
- Systematic internal transcribed spacer sequence analysis for identification of clinical mold isolates in diagnostic mycology: a 5-year study.Journal of clinical microbiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present report, we describe the first case of a phaeohyphomycotic brain abscess in a 5-year-old boy with chronic granulomatous disease (CGD) admitted to hospital with seizures. A computed tomography (CT) scan revealed a cerebral abscess and the microbiology study showed a dark, melanin-pigmented fungus, exhibiting only sterile hyphae. This fungus was identified by the amplification and sequencing of the 5.8S RNA gene and of the adjacent internal transcriber spacer domains, ITS1 and ITS2, as Alternaria infectoria. Due to the impossibility of a surgical excision, and although several therapeutic strategies were attempted, the patient died. Limitations in the routine identification procedures and therapeutic options of this emerging opportunistic agent are highlighted in this report.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.