Evidence map›Paper›PMID 18815294›Full record

ArticleJournal of virology2008

Phylogenetic analysis of the species Theilovirus: emerging murine and human pathogens.

Zhiguo Liang, A S Manoj Kumar, Morris S Jones, Nick J Knowles, Howard L Lipton

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 75 citations in OpenAlex.

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  5. ITAFProceedings of the National Academy of Sciences of the United States of America · 2025
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  16. A novel cardiovirus in wild rats.Virology journal · 2018
    Article
  17. Article
  18. Saffold virus, an emerging human cardiovirus.Reviews in medical virology · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Zhiguo LiangDepartment of Neurology and Rehabilitation Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.
A S Manoj Kumar
Morris S Jones
Nick J Knowles
Howard L Lipton
David Grant USAF Medical Center · USReliance Industries (India) · INThe Pirbright Institute · GBUniversity of Illinois Chicago · US

Funding

THEILERS VIRUS-INDUCED DEMYELINATING DISEASER01NS021913 · NINDS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LIPTON, HOWARD LEE · 1985 to 2010
$3.4M
NINDS NIH HHS R01 NS021913
6 · The paper itself

Abstract

The Cardiovirus genus of the family Picornaviridae includes two distinct species, Encephalomyocarditis virus and Theilovirus. We now report the complete nucleotide sequences of three Theiler's murine encephalomyelitis virus (TMEV) strains (TO Yale, TOB15, and Vie 415HTR) and of Vilyuisk human encephalomyelitis virus (VHEV). This information, together with the recently reported sequences of divergent theiloviruses (Theiler's-like rat virus [TRV] and Saffold viruses 1 and 2 [SAFV-1 and SAFV-2]), enables an updated phylogenetic analysis as well as a reexamination of several gene products important in the pathogenesis of this emerging group of viruses. In the light of the known neurotropism of TMEV and the new human SAFV-1 and SAFV-2, the resulting data suggest the existence of theiloviruses that cause human central nervous system infections. Our phylogenetic analyses point to the classification of presently known theiloviruses into five types: TMEV, VHEV, TRV, SAFV-1, and SAFV-2.

Indexed as

AnimalsCapsidCells, CulturedCricetinaeEpitopes, T-LymphocyteGenome, ViralHumansMicePhylogenyRecombination, GeneticTheilovirusUntranslated RegionsViral Nonstructural ProteinsEpitopes, T-LymphocyteUntranslated RegionsViral Nonstructural Proteins

Identifiers

PMID18815294
PMCPMC2583687
OpenAlexW2125959644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.