ReviewJournal of bioenergetics and biomembranes2008
Mitochondria in malaria and related parasites: ancient, diverse and streamlined.
Review in Journal of bioenergetics and biomembranes, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Malate dehydrogenase in parasitic protozoans: roles in metabolism and potential therapeutic applications.Essays in biochemistry · 2024Review
- Unique Properties of Apicomplexan Mitochondria.Annual review of microbiology · 2023Review
- Erythrocyte membrane with CLIPPKF as biomimetic nanodecoy traps merozoites and attaches to infected red blood cells to prevent Plasmodium infection.Journal of nanobiotechnology · 2023Article
- Parasite powerhouse: A review of the Toxoplasma gondii mitochondrion.The Journal of eukaryotic microbiology · 2022Review
- Properties of Plasmodium falciparum with a Deleted Apicoplast DNA Gyrase.Antimicrobial agents and chemotherapy · 2021Article
- A Yeast-Based Drug Discovery Platform To Identify Plasmodium falciparum Type II NADH Dehydrogenase Inhibitors.Antimicrobial agents and chemotherapy · 2021Article
- Effects and Mechanism of Action of Artemisinin on Mitochondria of Plasmodium berghei.Chinese journal of integrative medicine · 2020Article
- An overview of structure, function, and regulation of pyruvate kinases.Protein science : a publication of the Protein Society · 2019Review
- A unique dynamin-related protein is essential for mitochondrial fission in Toxoplasma gondii.PLoS pathogens · 2019Article
- Treatment of Toxoplasmosis and Neosporosis in Farm Ruminants: State of Knowledge and Future Trends.Current topics in medicinal chemistry · 2018Review
- Article
- Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.The Journal of experimental medicine · 2016Article
- The molecular and cellular action properties of artemisinins: what has yeast told us?Microbial cell (Graz, Austria) · 2016Review
- Oxidative stress generated during monensin treatment contributes to altered Toxoplasma gondii mitochondrial function.Scientific reports · 2016Article
- Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons.Biochemical pharmacology · 2015Article
- Isoprenoid metabolism in apicomplexan parasites.Current clinical microbiology reports · 2014Article
- Arrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase.The Journal of biological chemistry · 2011Article
- Tetrapyrrole synthesis of photosynthetic chromerids is likely homologous to the unusual pathway of apicomplexan parasites.The Plant cell · 2011Article
- Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function.Eukaryotic cell · 2011Article
- Physiological uncoupling of mitochondrial oxidative phosphorylation. Studies in different yeast species.Journal of bioenergetics and biomembranes · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Parasitic organisms have emerged from nearly every corner of the eukaryotic kingdom and hence display tremendous diversity of form and function. This diversity extends to their mitochondria and mitochondrion-derived organelles. While the principles of the chemiosmotic theory apply to all these pathogens, the differences from their hosts provide opportunities for therapeutic development. In this review we discuss examples of mitochondrial systems from a deep-branching phylum, Apicomplexa. Many important human pathogens, such as malaria parasites, belong to this phylum. Unique features of their mitochondria are validated targets for drugs that are selectively toxic to the parasites.
Indexed as
Identifiers
18814021What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.