Evidence map›Paper›PMID 18814016›Full record

Trial reportSurgical endoscopy2009

Epidural analgesia diminished pain but did not otherwise improve enhanced recovery after laparoscopic sigmoidectomy: a prospective randomized study.

Pertti Turunen, Monika Carpelan-Holmström, Pekka Kairaluoma, Heidi Wikström, Olli Kruuna, Pertti Pere, Martina Bachmann, Seppo Sarna, Tom Scheinin

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02086123 (Randomized Clinical Trial Comparing the Use of Perioperative Epidural Analgesia to Conventional Intravenous Narcotics and NSAIDS for Patients Undergoing Laparoscopic Colorectal Resection), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02086123 nacompletednot on this mapstarted 2012, after this paper: background citation

Randomized Clinical Trial Comparing the Use of Perioperative Epidural Analgesia to Conventional Intravenous Narcotics and NSAIDS for Patients Undergoing Laparoscopic Colorectal Resection

TypeinterventionalSponsorUniversity of California, IrvineRan2012 to 2015Enrolled87ConditionsPain, PostoperativeArmsEpidural Analgesia, Parenteral Analgesia (Intravenous)
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
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  13. Review
  14. Use of Epidural Analgesia in Sigmoidectomy: Is There Any Advantage in the Era of Minimally Invasive Surgery?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Observational
  15. Review
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  17. Article
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  20. A nationwide analysis of the use and outcomes of epidural analgesia in open colorectal surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pertti TurunenDepartment of Gastroenterological and General Surgery, Helsinki University Central Hospital, P.O. Box 900, 00029, Helsinki, Finland. pertti.turunen@hus.fi
Monika Carpelan-Holmström
Pekka Kairaluoma
Heidi Wikström
Olli Kruuna
Pertti Pere
Martina Bachmann
Seppo Sarna
Tom Scheinin
Helsinki University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe primary hypothesis for this study was that epidural analgesia reduces the use of opioids and thus advances bowel function and oral intake and shortens hospital stay after laparoscopic sigmoidectomy performed according to principles of enhanced recovery after surgery.

methodsFor this study, 60 patients with complicated diverticular disease were randomized to the epidural anesthesia group or the control group before surgery. Postoperative oxycodone consumption, pain, and recovery parameters were followed for 14 days.

resultsThe epidural group needed less oxycodone than the control group until 12 h postoperatively. They experienced significantly less pain related to coughing and motion until postoperative day 2. In the epidural group, fewer patients experienced significant pain, and the duration of postoperative pain was shorter. Postoperative oral intake, bowel function, hospital stay, and overall complication rate were similar in the two groups. However, the control group had more postoperative hematomas.

conclusionsEpidural analgesia significantly alleviates pain, reducing the need for opioids during the first 48 h after laparoscopic sigmoidectomy. However, epidural analgesia does not alter postoperative oral intake, mobilization, or length of hospital stay.

Indexed as

Analgesia, EpiduralColon, SigmoidAdultAgedAnalgesics, OpioidColectomyDiverticulum, ColonFemaleHumansLaparoscopyLength of StayMaleMiddle AgedOxycodonePostoperative PainProspective StudiesAnalgesics, OpioidOxycodone

Identifiers

PMID18814016
OpenAlexW2000105284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.