Evidence map›Paper›PMID 18813971›Full record

ArticleWorld journal of surgery2008

Risk factors for lateral cervical lymph node involvement in follicular thyroid carcinoma.

Haitham Alfalah, Isaac Cranshaw, Thomas Jany, Laurent Arnalsteen, Emmanuelle Leteurtre, Catherine Cardot, François Pattou, Bruno Carnaille

Abstract read
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In one paragraph

Article in World journal of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer.Thyroid : official journal of the American Thyroid Association · 2015
    Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Differentiated and Medullary Thyroid Cancer: Surgical Management of Cervical Lymph Nodes.Clinical oncology (Royal College of Radiologists (Great Britain)) · 2017
    Review
  7. Article
  8. Article
  9. Article
  10. [Minimally invasive follicular thyroid carcinoma : Not always total thyroidectomy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Haitham AlfalahDepartment of Endocrine Surgery, University Hospital, 59037, Lille, France.
Isaac Cranshaw
Thomas Jany
Laurent Arnalsteen
Emmanuelle Leteurtre
Catherine Cardot
François Pattou
Bruno Carnaille
Université de Lille · FRHôpital Claude Huriez · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetastases from follicular thyroid carcinoma (FTC) are usually blood borne and far less to lymph nodes (LN). The present study was designed to evaluate the factors that are associated with LN metastases in patients operated on for FTC.

methodsA retrospective review of 70 patients (25 men; mean age, 47 (range, 14-92) years) operated on between January 1995 and December 2005 for FTC was undertaken. All patients had histopathology study of the regional LN and postoperative radioiodine scintigraphy. According to LN invasion, they were divided into two groups in which various parameters were compared.

resultsThe length of follow-up was 52 (range 17-108) months. A total of 375 LN were examined from ipsilateral neck side and 87 LN from the contralateral side. LN metastases were found in five (7%) cases: all ipsilateral. Comparing data from the patients with and without LN metastases, respectively, age was 60 and 47 years (p = 0.12), male/female ratio was 1/4 and 24/41 (p = 0.44), tumor size was 68 and 37 mm (p < 0.01), tumor differentiation (well/moderate) was 3/2 and 25/19 (p = 0.89), distant metastases were detected in 1 and 8 cases (p = 0.72) .The tumor size was >40 mm in 35 (50%) patients. All patients with LN metastases were found in this group (5/35; 14%).

conclusionsFollicular thyroid carcinoma results in metastases to regional lymph nodes in 7% of cases but only to the ipsilateral neck side. Tumor size is the only factor that impacts it. We do not recommend lymph node dissection in follicular thyroid carcinomas <4 cm.

Indexed as

Adenocarcinoma, FollicularAdolescentAdultAgedAged, 80 and overCohort StudiesFemaleHumansLymphatic MetastasisLymph Node ExcisionMaleMiddle AgedNeckNeoplasm InvasivenessRetrospective StudiesRisk Factors

Identifiers

PMID18813971
OpenAlexW2061280187

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.