ArticleCiencia & saude coletiva
Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential.
Article in Ciencia & saude coletiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- The associations of air pollution exposure during pregnancy with fetal growth and anthropometric measurements at birth: a systematic review and meta-analysis.Environmental science and pollution research international · 2019Pooled it
- Association of PMPaediatric and perinatal epidemiology · 2025Article
- Susceptible windows of prenatal and postnatal fine particulate matter exposures and attention-deficit hyperactivity disorder symptoms in early childhood.The Science of the total environment · 2024Article
- Susceptible windows of exposure to fine particulate matter and fetal growth trajectories in the Spanish INMA (INfancia y Medio Ambiente) birth cohort.Environmental research · 2023Article
- Maternal exposure to ambient fine particulate matter and risk of premature rupture of membranes in Wuhan, Central China: a cohort study.Environmental health : a global access science source · 2019Article
- Associations of gestational and the first year of life exposure to ambient air pollution with childhood eczema in Hubei, China.Environmental science and pollution research international · 2019Article
- Demographic Inequities in Health Outcomes and Air Pollution Exposure in the Atlanta Area and its Relationship to Urban Infrastructure.Journal of urban health : bulletin of the New York Academy of Medicine · 2019Article
- Ambient Air Pollution Exposure and Fecundability in Women Undergoing In Vitro Fertilization.Environmental epidemiology (Philadelphia, Pa.) · 2019Article
- Impact of Maternal Air Pollution Exposure on Children's Lung Health: An Indian Perspective.Toxics · 2018Review
- Early-life exposure to indoor air pollution or tobacco smoke and lower respiratory tract illness and wheezing in African infants: a longitudinal birth cohort study.The Lancet. Planetary health · 2017Article
- Environmental chemicals and preterm birth: Biological mechanisms and the state of the science.Current epidemiology reports · 2017Article
- Ozone and Other Air Pollutants and the Risk of Congenital Heart Defects.Scientific reports · 2016Article
- Impact of the 2008 Beijing Olympics on the risk of pregnancy complications.Archives of environmental & occupational health · 2016Article
- Maternal exposure to air pollutant PM2.5 and PM10 during pregnancy and risk of congenital heart defects.Journal of exposure science & environmental epidemiology · 2016Article
- Additive Interaction between Heterogeneous Environmental Quality Domains (Air, Water, Land, Sociodemographic, and Built Environment) on Preterm Birth.Frontiers in public health · 2016Article
- Ambient air pollution and adverse birth outcomes: a natural experiment study.Population health metrics · 2015Article
- Effects of maternal exposure to ultrafine carbon black on brain perivascular macrophages and surrounding astrocytes in offspring mice.PloS one · 2014Article
- The relationship of air pollution and surrogate markers of endothelial dysfunction in a population-based sample of children.BMC public health · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article has three objectives: to describe the biologically plausible mechanistic pathways by which exposure to particulate matter (PM) may lead to adverse perinatal outcomes of low birth weight (LBW), intrauterine growth retardation (IUGR), and preterm delivery (PTD); review evidence showing that nutrition affects biologic pathways; and explain mechanisms by which nutrition may modify the impact of PM exposure on perinatal outcomes. We propose an interdisciplinary framework that brings together maternal and infant nutrition, air pollution exposure assessment, and cardiopulmonary and perinatal epidemiology. Five possible biologic mechanisms have been put forth in the emerging environmental sciences literature and provide corollaries for the proposed framework. The literature indicates that the effects of PM on LBW, PTD, and IUGR may manifest through the cardiovascular mechanisms of oxidative stress, inflammation, coagulation, endothelial function, and hemodynamic responses. PM exposure studies relating mechanistic pathways to perinatal outcomes should consider the likelihood that biologic responses and adverse birth outcomes may be derived from both PM and non-PM sources. We present strategies for empirically testing the proposed model and developing future research efforts.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.