Evidence map›Paper›PMID 18813294›Full record

ReviewNature reviews. Molecular cell biology2008

Phagosome maturation: going through the acid test.

Jason M Kinchen, Kodi S Ravichandran

Abstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 280 papers.

0numbers the graph read from it
0cells of the map it votes in
280citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

280 citing papers in PubMed, 549 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Secreted proteins ofFrontiers in tuberculosis · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
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  18. Review
  19. Article
  20. Article

220 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jason M KinchenBeirne B. Carter Center for Immunology Research and the Department of Microbiology, University of Virginia, Charlottesville, Virginia 22902, USA. kinchen@virginia.edu
Kodi S Ravichandran
Carter Center · US

Funding

Role of ELMO and DOCK 180 in signaling to engulfmentR01GM064709 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LORENZ, ULRIKE, RAVICHANDRAN, KODI S · 2003 to 2016
$3.6M
Phagocytosis of apoptotic cells: Signaling via GULPR01GM069998 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI RAVICHANDRAN, KODI S · 2004 to 2007
$953k
NIGMS NIH HHS R01 GM064709NIGMS NIH HHS R01 GM069998
6 · The paper itself

Abstract

Phagosome maturation is the process by which internalized particles (such as bacteria and apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound structures, leading to particle degradation. The characterization of the phagosomal proteome and studies in model organisms and mammals have led to the identification of numerous candidate proteins that cooperate to control the maturation of phagosomes containing different particles. A subset of these candidate proteins makes up the first pathway to be identified for the maturation of apoptotic cell-containing phagosomes. This suggests that a machinery that is distinct from receptor-mediated endocytosis is used in phagosome maturation.

Indexed as

AnimalsApoptosisEndocytosisHumansModels, BiologicalPhagocytesPhagocytosisPhagosomesProteomicsrab GTP-Binding ProteinsSignal TransductionToll-Like ReceptorsVacuolar Proton-Translocating ATPasesrab GTP-Binding ProteinsToll-Like ReceptorsVacuolar Proton-Translocating ATPases

Identifiers

PMID18813294
PMCPMC2908392
OpenAlexW2041112864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.