Evidence map›Paper›PMID 18809095›Full record

ReviewSeminars in hematology2008

Unexplained anemia in the elderly.

Sasan Makipour, Bindu Kanapuru, William B Ershler

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in hematology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 107 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Association between Anemia Severity and Ischemic Stroke Incidence: A Retrospective Cohort Study.International journal of environmental research and public health · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Iron Regulation in Elderly Asian Elephants (Frontiers in veterinary science · 2020
    Article
  14. Article
  15. Prevalence of Nutritional Anemia and Hyperhomocysteinemia in Urban Elderly.Indian journal of clinical biochemistry : IJCB · 2019
    Article
  16. Observational
  17. Article
  18. Article
  19. Review
  20. Aging, hematopoiesis, and the myelodysplastic syndromes.Hematology. American Society of Hematology. Education Program · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sasan MakipourClinical Research Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.
Bindu Kanapuru
William B Ershler
Institute on Aging · USNational Institute on Aging · US

Funding

Understanding Late Life AnemiaZIAAG000969 · NIA · NATIONAL INSTITUTE ON AGING · PI EGAN, JOSEPHINE · 2009 to 2025
$2.1M
Frailty Assessment and InterventionZIAAG000968 · NIA · NATIONAL INSTITUTE ON AGING · PI ERSHLER, WILLIAM · 2009 to 2010
$706k
Understanding Late Life AnemiaZ01AG000969 · NIA · NATIONAL INSTITUTE ON AGING · PI ERSHLER, WILLIAM · 2008 to 2008
$57k
Intramural NIH HHS Z01 AG000969
6 · The paper itself

Abstract

Among the elderly, anemia occurs with increasing frequency with each advancing decade. Unlike when anemia occurs in younger adults, the cause of anemia in the elderly is oftentimes not readily apparent or attributable to a single cause. However, this commonly observed form of anemia in the elderly (termed unexplained anemia [UA]) can generally be dissected to its root causes, which include renal insufficiency, inflammation, testosterone deficiency, and stem cell proliferative decline. Myelodysplasia (MDS) occurs commonly in this age group but can and should, for both diagnostic and therapeutic considerations, be distinguished from UA.

Indexed as

AgingAdultAgedAndrogensAnemiaCellular SenescenceCytokinesErythropoietinHematopoietic Stem CellsHumansInflammationRecombinant ProteinsRenal InsufficiencyAndrogensCytokinesErythropoietinRecombinant Proteins

Identifiers

PMID18809095
PMCPMC2586804
OpenAlexW1987761755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.