ArticleOrganic letters2008
Convergent and general one-step DNA-catalyzed synthesis of multiply branched DNA.
Article in Organic letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 23 citations in OpenAlex.
- Directed assembly of single-stranded DNA fragments for data storage via protein-free catalytic splint ligation.Nucleic acids research · 2025Article
- Improved deoxyribozymes for synthesis of covalently branched DNA and RNA.Nucleic acids research · 2011Article
- DNA as a versatile chemical component for catalysis, encoding, and stereocontrol.Angewandte Chemie (International ed. in English) · 2010Review
- Deoxyribozymes: selection design and serendipity in the development of DNA catalysts.Accounts of chemical research · 2009Review
- Use of deoxyribozymes in RNA research.Methods in enzymology · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
We report a deoxyribozyme (DNA enzyme) that catalyzes the convergent and general synthesis of branched DNA. The 15HA9 deoxyribozyme mediates nucleophilic attack of the 2'-hydroxyl group of a ribonucleotide embedded within one DNA substrate into a 5'-adenylate of the second DNA substrate. This approach can be used to synthesize multiply branched DNA with a wide range of DNA sequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.