ArticleBritish journal of pharmacology2008
Peroxynitrite: in vivo cardioprotectant or arrhythmogen?
Article in British journal of pharmacology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Myocardial reperfusion injury and oxidative stress: Therapeutic opportunities.World journal of cardiology · 2018Review
- Molecular basis of cardioprotective effect of antioxidant vitamins in myocardial infarction.BioMed research international · 2013Review
- Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage.Disease markers · 2013Review
- Bio-tea prevents membrane destabilization during Isoproterenol-induced myocardial injury.Journal of microscopy and ultrastructureArticle
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
The factors that determine susceptibility to lethal ventricular arrhythmias during myocardial ischaemia and reperfusion in vivo are complex, but the balance between proarrhythmic and antiarrhythmic endogenous substances is likely to be important. However, in this context, it is not well established what effect endogenously produced peroxynitrite has on arrhythmias that develop during ischaemia/reperfusion in vivo. The study by Kiss et al., published in this issue of the BJP, provides some insights to this problem. We discuss the wider implications of this study as well as issues that still require resolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.