ArticleApplied and environmental microbiology2008
Gene expression profiling of Listeria monocytogenes strain F2365 during growth in ultrahigh-temperature-processed skim milk.
Article in Applied and environmental microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 62 citations in OpenAlex.
- The type of food influences the behaviour of Listeria monocytogenes in a food-gastrointestinal-infection model.NPJ science of food · 2025Article
- Investigating the role of theFEMS microbes · 2025Article
- Comparative Gene Expression Analysis ofMicroorganisms · 2024Article
- Involvement of a putative ATP-Binding Cassette (ABC) Involved in manganese transport in virulence of Listeria monocytogenes.PloS one · 2022Article
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- Transcriptomic Analysis of the Adaptation ofFrontiers in microbiology · 2017Article
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- Fluorescence-based bioassays for the detection and evaluation of food materials.Sensors (Basel, Switzerland) · 2015Review
- Transcriptomic Analysis of the Adaptation of Listeria monocytogenes to Growth on Vacuum-Packed Cold Smoked Salmon.Applied and environmental microbiology · 2015Article
- Genetic characterization of plasmid-associated triphenylmethane reductase in Listeria monocytogenes.Applied and environmental microbiology · 2014Article
- Omics approaches in food safety: fulfilling the promise?Trends in microbiology · 2014Review
- The Capacity ofItalian journal of food safety · 2014Article
- Conservation and distribution of the benzalkonium chloride resistance cassette bcrABC in Listeria monocytogenes.Applied and environmental microbiology · 2013Article
- Gene expression profiling of a nisin-sensitive Listeria monocytogenes Scott A ctsR deletion mutant.Journal of industrial microbiology & biotechnology · 2013Article
- A novel restriction-modification system is responsible for temperature-dependent phage resistance in Listeria monocytogenes ECII.Applied and environmental microbiology · 2012Article
- Gene expression profiling of a pressure-tolerant Listeria monocytogenes Scott A ctsR deletion mutant.Journal of industrial microbiology & biotechnology · 2011Article
- Changes in gene expression during adaptation of Listeria monocytogenes to the soil environment.PloS one · 2011Article
- Genetic characterization of plasmid-associated benzalkonium chloride resistance determinants in a Listeria monocytogenes strain from the 1998-1999 outbreak.Applied and environmental microbiology · 2010Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To study how Listeria monocytogenes survives and grows in ultrahigh-temperature-processed (UHT) skim milk, microarray technology was used to monitor the gene expression profiles of strain F2365 in UHT skim milk. Total RNA was isolated from strain F2365 in UHT skim milk after 24 h of growth at 4 degrees C, labeled with fluorescent dyes, and hybridized to "custom-made" commercial oligonucleotide (35-mers) microarray chips containing the whole genome of L. monocytogenes strain F2365. Compared to L. monocytogenes grown in brain heart infusion (BHI) broth for 24 h at 4 degrees C, 26 genes were upregulated (more-than-twofold increase) in UHT skim milk, whereas 14 genes were downregulated (less-than-twofold decrease). The upregulated genes included genes encoding transport and binding proteins, transcriptional regulators, proteins in amino acid biosynthesis and energy metabolism, protein synthesis, cell division, and hypothetical proteins. The downregulated genes included genes that encode transport and binding proteins, protein synthesis, cellular processes, cell envelope, energy metabolism, a transcriptional regulator, and an unknown protein. The gene expression changes determined by microarray assays were confirmed by real-time reverse transcriptase PCR analyses. Furthermore, cells grown in UHT skim milk displayed the same sensitivity to hydrogen peroxide as cells grown in BHI, demonstrating that the elevated levels of expression of genes encoding manganese transporter complexes in UHT skim milk did not result in changes in the oxidative stress sensitivity. To our knowledge, this report represents a novel study of global transcriptional gene expression profiling of L. monocytogenes in a liquid food.
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