ReviewLancet (London, England)2008
Complexity of chronic asthma and chronic obstructive pulmonary disease: implications for risk assessment, and disease progression and control.
Review in Lancet (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE).Environmental health perspectives · 2015Pooled it
- Fluctuation Analysis of Peak Expiratory Flow and Its Association with Treatment Failure in Asthma.American journal of respiratory and critical care medicine · 2017Trial
- Disease Burden of Asthma Patients Utilizing Short-Acting Beta-2 Agonist-Only Inhalers as Rescue in the United States.Journal of asthma and allergy · 2026Article
- Short-term Frailty Index Fluctuations in Older Adults: Noise or Signal?The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- A Fully Decentralized Randomized Controlled Study of As-Needed Albuterol-Budesonide Fixed-Dose Inhaler in Mild Asthma: The BATURA Study Design.Journal of asthma and allergy · 2024Article
- Genomics of Treatable Traits in Asthma.Genes · 2023Review
- Housing typologies and asthma: a scoping review.BMC public health · 2023Article
- A stochastic mixed effects model to assess treatment effects and fluctuations in home-measured peak expiratory flow and the association with exacerbation risk in asthma.CPT: pharmacometrics & systems pharmacology · 2022Article
- Personalization of Conversational Agent-Patient Interaction Styles for Chronic Disease Management: Two Consecutive Cross-sectional Questionnaire Studies.Journal of medical Internet research · 2021Article
- Conversational Agents as Mediating Social Actors in Chronic Disease Management Involving Health Care Professionals, Patients, and Family Members: Multisite Single-Arm Feasibility Study.Journal of medical Internet research · 2021Article
- Deliberative and Paternalistic Interaction Styles for Conversational Agents in Digital Health: Procedure and Validation Through a Web-Based Experiment.Journal of medical Internet research · 2021Article
- Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients.Pharmaceutics · 2020Article
- Fluctuation-based clustering reveals phenotypes of patients with different asthma severity.ERJ open research · 2020Article
- Observational
- Airway Transmural Pressures in an Airway Tree During Bronchoconstriction in Asthma.Journal of engineering and science in medical diagnostics and therapy · 2019Article
- COPD stands for complex obstructive pulmonary disease.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- Effect of Rho-kinase inhibition on complexity of breathing pattern in a guinea pig model of asthma.PloS one · 2017Article
- Systems Biology and Clinical Practice in Respiratory Medicine. The Twain Shall Meet.American journal of respiratory and critical care medicine · 2016Article
- Why understanding the asthma chronic obstructive pulmonary disease overlap syndrome (ACOS) is important to the clinician.The Indian journal of medical research · 2016Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Although assessment of asthma control is important to guide treatment, it is difficult since the temporal pattern and risk of exacerbations are often unpredictable. In this Review, we summarise the classic methods to assess control with unidimensional and multidimensional approaches. Next, we show how ideas from the science of complexity can explain the seemingly unpredictable nature of bronchial asthma and emphysema, with implications for chronic obstructive pulmonary disease. We show that fluctuation analysis, a method used in statistical physics, can be used to gain insight into asthma as a dynamic disease of the respiratory system, viewed as a set of interacting subsystems (eg, inflammatory, immunological, and mechanical). The basis of the fluctuation analysis methods is the quantification of the long-term temporal history of lung function parameters. We summarise how this analysis can be used to assess the risk of future asthma episodes, with implications for asthma severity and control both in children and adults.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.