Evidence map›Paper›PMID 18804756›Full record

ArticleCarbohydrate research2008

The structure of the L9 immunotype lipooligosaccharide from Neisseria meningitidis NMA Z2491.

Biswa Choudhury, Charlene M Kahler, Anup Datta, David S Stephens, Russell W Carlson

Open access · greenAbstract read
In one paragraph

Article in Carbohydrate research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Frontiers in immunology · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Biswa ChoudhuryComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, USA.
Charlene M Kahler
Anup Datta
David S Stephens
Russell W Carlson
University of Georgia · USEmory University · USUniversity of Western Australia · AU

Funding

MENINGOCOCCAL LIPOOLIGOSACCHARIDE &MUCOSAL PATHOGENESISR01AI033517 · NIAID · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 1993 to 2007
$1.7M
NIAID NIH HHS R01 AI033517NIAID NIH HHS R01AI033517
6 · The paper itself

Abstract

The lipooligosaccharide (LOS) from the Neisseria meningitidis prototype serogroup A strain NMA Z2491, an L9 immunotype LOS, was isolated and structurally characterized using glycosyl composition and linkage determination, mass spectrometry, and both 1- and 2-D nuclear resonance spectroscopy. The results show that the L9 LOS has an identical structure to that of an L4 LOS structure with the exception that it does not contain a sialic acid residue linked to position 3 of the lactoneotetraose terminal galactosyl residue. Further, two oligosaccharides are present in the Z2491 LOS preparation, OS1 and OS2. They differ from one another only in that OS2 contains an added glycine moiety, presumably at O-7 on the inner core Hep II residue. The structures of these oligosaccharides are as follows: where R=H or Gly.

Indexed as

Antigens, BacterialCarbohydrate SequenceGas Chromatography-Mass SpectrometryHumansHydrolysisLauric AcidsLipopolysaccharidesMeningitis, MeningococcalMolecular Sequence DataMyristic AcidNeisseria meningitidisOligosaccharidesAntigens, Bacteriallauric acidLauric Acidslipid-linked oligosaccharidesLipopolysaccharidesMyristic AcidOligosaccharides

Identifiers

PMID18804756
PMCPMC2784147
OpenAlexW2023003265

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.