ArticleBreast cancer research : BCR2008
Menopausal hormone therapy in relation to breast cancer characteristics and prognosis: a cohort study.
Article in Breast cancer research : BCR, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 52 citations in OpenAlex.
- Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trial.The Lancet. Oncology · 2012Trial
- Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women.JAMA · 2010Trial
- Effect of the use of hormonal replacement therapy on breast cancer prognosis: A systematic review and meta-analysis.Oncology letters · 2026Article
- Characteristics and Prognosis of Breast Cancer Patients With Prior Hormone Replacement Therapy: Insights From the Korean Breast Cancer Society Registry.Journal of breast cancer · 2024Article
- Menopausal hormone therapy and incidence, mortality, and survival of breast cancer subtypes: a prospective cohort study.Breast cancer research : BCR · 2024Article
- The association of breast cancer patients survival and prior menopausal hormone therapy in women with type 2 diabetes.Scientific reports · 2024Article
- A natural history and copula-based joint model for regional and distant breast cancer metastasis.Statistical methods in medical research · 2022Article
- Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data.Statistical methods in medical research · 2022Observational
- Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Article
- Prognostic Impact of Menopausal Hormone Therapy in Breast Cancer Differs According to Tumor Characteristics and Treatment.Frontiers in oncology · 2020Article
- Joint models of tumour size and lymph node spread for incident breast cancer cases in the presence of screening.Statistical methods in medical research · 2019Article
- Family history influences the tumor characteristics and prognosis of breast cancers developing during postmenopausal hormone therapy.Familial cancer · 2018Article
- Breast cancer tumour growth modelling for studying the association of body size with tumour growth rate and symptomatic detection using case-control data.Breast cancer research : BCR · 2015Article
- Hormone Therapy and its Effect on the Prognosis in Breast Cancer Patients.Geburtshilfe und Frauenheilkunde · 2015Article
- Menopausal hormone therapy and breast cancer mortality: clinical implications.Therapeutic advances in drug safety · 2015Review
- Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry.British journal of cancer · 2014Article
- Mammographic density reduction is a prognostic marker of response to adjuvant tamoxifen therapy in postmenopausal patients with breast cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013Article
- Estrogen plus progestin and breast cancer incidence and mortality in the Women's Health Initiative Observational Study.Journal of the National Cancer Institute · 2013Article
- Changing concepts: Menopausal hormone therapy and breast cancer.Journal of the National Cancer Institute · 2012Review
- Breast tumor characteristics in hormone replacement therapy users.Pathology oncology research : POR · 2011Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMenopausal hormone therapy has been reported to increase the risk of certain subtypes of breast cancer and to be associated with a favorable survival. These associations could either be due to an increased mammographic surveillance or to a biological effect. We assessed these associations in a Swedish cohort of postmenopausal breast cancer patients holding information on mammographic examinations, menopausal hormone therapy use, other breast cancer risk factors, and cancer treatment.
methodsWe analyzed 2,660 postmenopausal women aged 50 to 74 years, diagnosed with invasive breast cancer in 1993 to 1995 and followed until the end of 2003 (median follow-up, 9 years and 3 months). We assessed the influence of hormone therapy before diagnosis on tumor characteristics and breast cancer-specific survival. We analyzed hormone therapy before diagnosis by regimen (estrogen-progestin therapy or estrogen alone therapy), recency (current or past), and duration of use (<5 years or > or = 5 years).
resultsCurrent use, but not past use, compared with never use of hormone therapy before diagnosis seemed to be associated with tumors of low grade and with improved breast cancer-specific survival. The associations were stronger with longer duration, but did not vary significantly by regimen. The favorable survival among current users of hormone therapy was only partly explained by differences in available tumor characteristics and mammographic surveillance.
conclusionsWe conclude that current menopausal hormone therapy, especially long term, is associated with favorable tumor characteristics and survival.
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