ArticleNano letters2008
Encapsulation of semiconducting polymers in vault protein cages.
Article in Nano letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Addressing Critical Issues Related to Storage and Stability of the Vault Nanoparticle Expressed and Purified fromInternational journal of molecular sciences · 2023Article
- Polyelectrolyte Encapsulation and Confinement within Protein Cage-Inspired Nanocompartments.Pharmaceutics · 2021Review
- Review
- Enzyme encapsulation by protein cages.RSC advances · 2020Review
- Protein cage assembly across multiple length scales.Chemical Society reviews · 2018Review
- Article
- Smart vaults: thermally-responsive protein nanocapsules.ACS nano · 2013Article
- In silico resurrection of the major vault protein suggests it is ancestral in modern eukaryotes.Genome biology and evolution · 2013Article
- Vault nanoparticles engineered with the protein transduction domain, TAT48, enhances cellular uptake.Integrative biology : quantitative biosciences from nano to macro · 2013Article
- Targeted vault nanoparticles engineered with an endosomolytic peptide deliver biomolecules to the cytoplasm.ACS nano · 2011Article
- Vaults engineered for hydrophobic drug delivery.Small (Weinheim an der Bergstrasse, Germany) · 2011Article
- Vaults are dynamically unconstrained cytoplasmic nanoparticles capable of half vault exchange.ACS nano · 2010Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We demonstrate that a semiconducting polymer [poly(2-methoxy-5-propyloxy sulfonate phenylene vinylene), MPS-PPV] can be encapsulated inside recombinant, self-assembling protein nanocapsules called "vaults". Polymer incorporation into these nanosized protein cages, found naturally at approximately 10,000 copies per human cell, was confirmed by fluorescence spectroscopy and small-angle X-ray scattering. Although vault cellular functions and gating mechanisms remain unknown, their large internal volume and natural prevalence within the human body suggests they could be used as carriers for therapeutics and medical imaging reagents. This study provides the groundwork for the use of vaults in encapsulation and delivery applications.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.