Trial reportPhysical therapy2008
Diabetes mellitus and gait dysfunction: possible explanatory factors.
Trial report in Physical therapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06713070 (Pattern of Gait Abnormality As a Predictor for Disease Progression in Dementia), which is not on this map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pattern of Gait Abnormality As a Predictor for Disease Progression in Dementia
Who cites it
40 citing papers in PubMed, 96 citations in OpenAlex.
- Association of Dual Decline in Cognition and Gait Speed With Risk of Dementia in Older Adults.JAMA network open · 2022Trial
- AI-Enhanced Modular Material Selection for Patient-Specific Diabetic Insoles via Silicone Molding.Human factors · 2026Article
- Reliability of Gait Analysis Using ORPHE ANALYTICS in Patients with Type 2 Diabetes: A Single-center Observational Study.JMA journal · 2025Article
- Balance, Gait, Functionality and Fall Occurrence in Adults and Older Adults with Type 2 Diabetes Mellitus and Associated Peripheral Neuropathy.Clinics and practice · 2024Article
- Could poor glycaemic control be a predictor of walking speed decline in older adults? Evidence from the English Longitudinal Study of Ageing.Diabetes, obesity & metabolism · 2024Article
- Associations of Neurological Biomarkers in Serum With Gait Measures: The Cardiovascular Health Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
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- "PNP slows down" - linearly-reduced whole body joint velocities and altered gait patterns in polyneuropathy.Frontiers in human neuroscience · 2023Article
- Cognitive function and cardiorespiratory fitness affect gait speed in type-2 diabetic patients without neuropathy.Croatian medical journal · 2022Article
- Is handgrip strength a useful tool to detect slow walking speed in older Indian adults: A cross-sectional study among geriatric outpatients in a tertiary care hospital in South India.Journal of frailty, sarcopenia and falls · 2022Article
- Sensory-Motor Mechanisms Increasing Falls Risk in Diabetic Peripheral Neuropathy.Medicina (Kaunas, Lithuania) · 2021Review
- Vascular health across young adulthood and midlife cerebral autoregulation, gait, and cognition.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Article
- Combined diabetes and arthritis are associated with declined gait speed.Clinical rheumatology · 2021Article
- The Influence of Diabetes on Multisensory Integration and Mobility in Aging.Brain sciences · 2021Article
- Long-Term Use of a Sensory Prosthesis Improves Function in a Patient With Peripheral Neuropathy: A Case Report.Frontiers in neurology · 2021Article
- A Wearable Gait Analysis System Used in Type 2 Diabetes Mellitus Patients: A Case-Control Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Article
- The Use of Posturography in Investigating the Risk of Falling in Frail or Prefrail Older People with Diabetes.The Journal of frailty & aging · 2020Observational
- What are the association patterns between handgrip strength and adverse health conditions? A topical review.SAGE open medicine · 2020Review
- Health Consequences of Sarcopenic Obesity: A Narrative Review.Frontiers in endocrinology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
objectiveGait characteristics differ in individuals with diabetes compared with those without diabetes. Limited information regarding potential explanatory factors for this association exists. This study examined the association between diabetes and gait characteristics in older adults and explored potential explanatory factors.
designA cross-sectional, observational study design was used.
methodsAt the 1998-1999 clinic visit, 558 ambulatory older adults (mean age=79 years) from the Pittsburgh site of the Cardiovascular Health Study had an assessment of their gait characteristics, diabetes, health status, cognition, mood, lower-extremity circulation and sensation, vision, lower-extremity strength (force-producing capacity), physical activity, and body mass index (BMI). A series of linear regression models were developed to examine the association between diabetes and gait characteristics and to examine potential explanatory factors for the associations.
resultsDiabetes was related to gait speed (beta=-.06 m/s); however, the association was partially explained by health status variables, cognition, mood, lower-extremity circulation and sensation, visual impairment, lower-extremity strength, physical activity, and BMI. Health status and lower-extremity strength each explained the greatest proportion of the association (beta reduced 66% by each). Diabetes was related to step width (beta=.02 m), and the association could not be explained by the examined factors.
conclusionsDiabetes was associated with gait alterations in older adults. Slowed gait speed appears to be secondary to the peripheral effect of the disease on other body systems. The effect of diabetes on step width was not explained in the analyses and may be related to peripheral motor nerve function or central influences of the disease, which could not be assessed in this study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.