Evidence map›Paper›PMID 18801851›Full record

Trial reportPhysical therapy2008

Comparison of combined aerobic and high-force eccentric resistance exercise with aerobic exercise only for people with type 2 diabetes mellitus.

Robin L Marcus, Sheldon Smith, Glen Morrell, Odessa Addison, Leland E Dibble, Donna Wahoff-Stice, Paul C Lastayo

Erratum issuedAbstract readClinical TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physical therapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

7 authors.

Robin L MarcusDepartment of Physical Therapy and Department of Exercise and Sport Science, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USA. robin.marcus@hsc.utah.edu
Sheldon Smith
Glen Morrell
Odessa Addison
Leland E Dibble
Donna Wahoff-Stice
Paul C Lastayo

Funding

Utah BIRCWH Career Development Program in Women's HealthK12HD043449 · NICHD · UNIVERSITY OF UTAH · PI BJORKMAN, DAVID JESS · 2002 to 2006
$2.3M
NICHD NIH HHS 5K12HD043449-04
6 · The paper itself

Abstract

background and purposeThe purpose of this study was to compare the outcomes between a diabetes exercise training program using combined aerobic and high-force eccentric resistance exercise and a program of aerobic exercise only. SUBJECTS AND

methodsFifteen participants with type 2 diabetes mellitus (T2DM) participated in a 16-week supervised exercise training program: 7 (mean age=50.7 years, SD=6.9) in a combined aerobic and eccentric resistance exercise program (AE/RE group) and 8 (mean age=58.5 years, SD=6.2) in a program of aerobic exercise only (AE group). Outcome measures included thigh lean tissue and intramuscular fat (IMF), glycosylated hemoglobin, body mass index (BMI), and 6-minute walk distance.

resultsBoth groups experienced decreases in mean glycosylated hemoglobin after training (AE/RE group: -0.59% [95% confidence interval (CI)=-1.5 to 0.28]; AE group: -0.31% [95% CI=-0.60 to -0.03]), with no significant between-group differences. There was an interaction between group and time with respect to change in thigh lean tissue cross-sectional area, with the AE/RE group gaining more lean tissue (AE/RE group: 15.1 cm(2) [95% CI=7.6 to 22.5]; AE group: -5.6 cm(2) [95% CI=-10.4 to 0.76]). Both groups experienced decreases in mean thigh IMF cross-sectional area (AE/RE group: -1.2 cm(2) [95% CI=-2.6 to 0.26]; AE group: -2.2 cm(2) [95% CI=-3.5 to -0.84]) and increases in 6-minute walk distance (AE/RE group: 45.5 m [95% CI=7.5 to 83.6]; AE group: 29.9 m [95% CI=-7.7 to 67.5]) after training, with no between-group differences. There was an interaction between group and time with respect to change in BMI, with the AE/RE group experiencing a greater decrease in BMI. DISCUSSION AND

conclusionSignificant improvements in long-term glycemic control, thigh composition, and physical performance were demonstrated in both groups after participating in a 16-week exercise program. SUBJECTS: in the AE/RE group demonstrated additional improvements in thigh lean tissue and BMI. Improvements in thigh lean tissue may be important in this population as a means to increase resting metabolic rate, protein reserve, exercise tolerance, and functional mobility.

Indexed as

Body Mass IndexDiabetes Mellitus, Type 2ExerciseExercise TherapyFemaleGlycated HemoglobinHumansMaleMiddle AgedGlycated Hemoglobin

Identifiers

PMID18801851
PMCPMC2579905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.