Evidence map›Paper›PMID 18801437›Full record

ReviewCurrent opinion in structural biology2008

Experimental approaches for solution X-ray scattering and fiber diffraction.

H Tsuruta, T C Irving

Abstract readReview
In one paragraph

Review in Current opinion in structural biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Diffraction Techniques in Structural Biology.Current protocols in nucleic acid chemistry · 2016
    Review
  2. Article
  3. Methods for SAXS-based structure determination of biomolecular complexes.Advanced materials (Deerfield Beach, Fla.) · 2014
    Article
  4. Article
  5. Reconstruction of SAXS Profiles from Protein Structures.Computational and structural biotechnology journal · 2013
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. RNA structure determination using SAXS data.The journal of physical chemistry. B · 2010
    Article
  11. Diffraction techniques in structural biology.Current protocols in nucleic acid chemistry · 2010
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

H TsurutaStanford Synchrotron Radiation Laboratory (SSRL), SLAC, Stanford University, MS69, Menlo Park, CA 94025, USA. tsuruta@stanford.edu
T C Irving

Funding

ZWITTERION SURFACTANT DDMAB FOR IMPROV STABIL OF PROTEINP41RR001209 · NCRR · STANFORD UNIVERSITY · PI GONZALEZ, ANA M · 1985 to 2011
$38.9M
X-RAY STUDIES OF NEUROFIBRILLARY TANGLES IN ALZHEIMER'S DISEASE BRAIN TISSUEP41RR008630 · NCRR · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2001 to 2011
$14.4M
Time resolved SAXS studies on the RP2/Arl3 complex pp.484-485P41GM103622 · NIGMS · ILLINOIS INSTITUTE OF TECHNOLOGY · PI IRVING, THOMAS C · 2012 to 2020
$11.9M
NCRR NIH HHS P41 RR001209NCRR NIH HHS P41 RR008630NCRR NIH HHS RR08630NIGMS NIH HHS P41 GM103622
6 · The paper itself

Abstract

X-ray scattering and diffraction from non-crystalline systems have gained renewed interest in recent years, as focus shifts from the structural chemistry information gained by high-resolution studies to the context of structural physiology at larger length scales. Such techniques permit the study of isolated macromolecules as well as highly organized macromolecular assemblies as a whole under near-physiological conditions. Time-resolved approaches, made possible by advanced synchrotron instrumentation, add a crucial dimension to many of these investigations. This article reviews experimental approaches in non-crystalline X-ray scattering and diffraction that may be used to illuminate important scientific questions such as protein/nucleic acid folding and structure-function relationships in large macromolecular assemblies.

Indexed as

AnimalsConnective TissueCrystallography, X-RayDrosophilaModels, MolecularMolecular ConformationNeutronsNucleic AcidsPharmaceutical SolutionsProtein ConformationProteinsScattering, RadiationSolutionsSynchrotronsX-Ray DiffractionNucleic AcidsPharmaceutical SolutionsProteinsSolutions

Identifiers

PMID18801437
PMCPMC2659704

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.