ArticleDevelopmental biology2008
Differential requirements of a mitotic acetyltransferase in somatic and germ line cells.
Article in Developmental biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Illuminating the impact of N-terminal acetylation: from protein to physiology.Nature communications · 2025Review
- Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction.Nature communications · 2023Article
- Characterisation and preliminary functional analysis of N-acetyltransferase 13 from Schistosoma japonicum.BMC veterinary research · 2021Article
- Characterization of SpecificACS medicinal chemistry letters · 2020Article
- Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion.Scientific reports · 2016Article
- Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling.Nature communications · 2016Article
- Crystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.Structure (London, England : 1993) · 2016Article
- Absence of N-terminal acetyltransferase diversification during evolution of eukaryotic organisms.Scientific reports · 2016Article
- Review
- Chemoproteomic profiling of lysine acetyltransferases highlights an expanded landscape of catalytic acetylation.Journal of the American Chemical Society · 2014Article
- Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development.eLife · 2014Article
- Arabidopsis CHROMOSOME TRANSMISSION FIDELITY 7 (AtCTF7/ECO1) is required for DNA repair, mitosis and meiosis.The Plant journal : for cell and molecular biology · 2013Article
- Protein N-terminal acetyltransferases in cancer.Oncogene · 2013Review
- Meiosis in male Drosophila.Spermatogenesis · 2012Article
- Human protein N-terminal acetyltransferase hNaa50p (hNAT5/hSAN) follows ordered sequential catalytic mechanism: combined kinetic and NMR study.The Journal of biological chemistry · 2012Article
- Structure of a ternary Naa50p (NAT5/SAN) N-terminal acetyltransferase complex reveals the molecular basis for substrate-specific acetylation.The Journal of biological chemistry · 2011Article
- NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation.PLoS genetics · 2011Article
- Proteome-derived peptide libraries allow detailed analysis of the substrate specificities of N(alpha)-acetyltransferases and point to hNaa10p as the post-translational actin N(alpha)-acetyltransferase.Molecular & cellular proteomics : MCP · 2011Article
- The human N-alpha-acetyltransferase 40 (hNaa40p/hNatD) is conserved from yeast and N-terminally acetylates histones H2A and H4.PloS one · 2011Article
- Drosophila variable nurse cells encodes arrest defective 1 (ARD1), the catalytic subunit of the major N-terminal acetyltransferase complex.Developmental dynamics : an official publication of the American Association of Anatomists · 2010Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
During mitosis different types of cells can have differential requirements for chromosome segregation. We isolated two new alleles of the separation anxiety gene (san). san was previously described in both Drosophila and in humans to be required for centromeric sister chromatid cohesion (Hou et al., 2007; Williams et al., 2003). Our work confirms and expands the observation that san is required in vivo for normal mitosis of different types of somatic cells. In addition, we suggest that san is also important for the correct resolution of chromosomes, implying a more general function of this acetyltransferase. Surprisingly, during oogenesis we cannot detect mitotic defects in germ line cells mutant for san. We hypothesize the female germ line stem cells have differential requirements for mitotic sister chromatid cohesion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.