Evidence map›Paper›PMID 18800223›Full record

ReviewHistochemistry and cell biology2008

Fluorescence fluctuations analysis in nanoapertures: physical concepts and biological applications.

Pierre-François Lenne, Hervé Rigneault, Didier Marguet, Jérôme Wenger

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histochemistry and cell biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pierre-François LenneInstitut Fresnel, UMR 6133 CNRS, Aix-Marseille University and Ecole Centrale Marseille, Domaine Universitaire de Saint Jérôme, 13397, Marseille Cedex 20, France. lenne@fresnel.fr
Hervé Rigneault
Didier Marguet
Jérôme Wenger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the past years, nanophotonics has provided new approaches to study the biological processes below the optical diffraction limit. How single molecules diffuse, bind and assemble can be studied now at the nanometric level, not only in solutions but also in complex and crowded environments such as in live cells. In this context fluorescence fluctuations spectroscopy is a unique tool since it has proven to be easy to use in combination with nanostructures, which are able to confine light in nanometric volumes. We review here recent advances in fluorescence fluctuations' analysis below the optical diffraction limit with a special focus on nanoapertures milled in metallic films. We discuss applications in the field of single-molecule detection, DNA sequencing and membrane organization, and underscore some potential perspectives of this new emerging technology.

Indexed as

Microscopy, FluorescenceMolecular Probe TechniquesSpectrometry, FluorescenceAnimalsEnzymesEquipment DesignFluorescent DyesHumansImage Processing, Computer-AssistedMembrane LipidsMembrane ProteinsMicroscopy, ConfocalNanotechnologySequence Analysis, DNAEnzymesFluorescent DyesMembrane LipidsMembrane Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.