Evidence map›Paper›PMID 18799586›Full record

ArticleJournal of virology2008

Utilization of DC-SIGN for entry of feline coronaviruses into host cells.

Andrew D Regan, Gary R Whittaker

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Feline Coronavirus Antivirals: A Review.Pathogens (Basel, Switzerland) · 2021
    Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Exploitation of glycosylation in enveloped virus pathobiology.Biochimica et biophysica acta. General subjects · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew D ReganDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Gary R Whittaker
Cornell University · US

Funding

TRAINING IN MOLECULAR VIROLOGY AND PATHOGENESIST32AI007618 · NIAID · CORNELL UNIVERSITY ITHACA · PI PARRISH, COLIN R. · 2000 to 2010
$1.4M
NIAID NIH HHS T32 AI007618NIAID NIH HHS T32AI007618
6 · The paper itself

Abstract

The entry and dissemination of viruses in several families can be mediated by C-type lectins such as DC-SIGN. We showed that entry of the serotype II feline coronavirus strains feline infectious peritonitis virus (FIPV) WSU 79-1146 and DF2 into nonpermissive mouse 3T3 cells can be rescued by the expression of human DC-SIGN (hDC-SIGN) and that infection of a permissive feline cell line (Crandall-Reese feline kidney) was markedly enhanced by the overexpression of hDC-SIGN. Treatment with mannan considerably reduced infection of feline monocyte-derived cells expressing DC-SIGN, indicating a role for FIPV infection in vivo.

Indexed as

3T3 CellsAnimalsCatsCD13 AntigensCell Adhesion MoleculesCoronavirus, FelineDC-Specific ICAM-3 Grabbing NonintegrinHumansLectins, C-TypeMannansMiceReceptors, Cell SurfaceCD13 AntigensCell Adhesion MoleculesDC-Specific ICAM-3 Grabbing NonintegrinLectins, C-TypeMannansReceptors, Cell Surface

Identifiers

PMID18799586
PMCPMC2583691
OpenAlexW2026103364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.