ReviewCurrent gastroenterology reports2008
Significance of serrated polyps of the colon.
Review in Current gastroenterology reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Association of Trainee Participation in Colonoscopy Procedures With Quality Metrics.JAMA network open · 2022Article
- Patient, Physician, and Procedure Characteristics Are Independently Predictive of Polyp Detection Rates in Clinical Practice.Digestive diseases and sciences · 2021Article
- Emerging trends in colorectal cancer: Dysregulated signaling pathways (Review).International journal of molecular medicine · 2021Article
- Postmenopausal Hormone Therapy and Colorectal Cancer Risk by Molecularly Defined Subtypes and Tumor Location.JNCI cancer spectrum · 2020Article
- Can the rate and location of sessile serrated polyps be part of colorectal Cancer disparity in African Americans?BMC gastroenterology · 2019Article
- Molecular phenotypes of colorectal cancer and potential clinical applications.Gastroenterology report · 2015Review
- Serrated polyps and their alternative pathway to the colorectal cancer: a systematic review.Gastroenterology research and practice · 2015Review
- Serrated neoplasia of the colon: what do we really know?Current gastroenterology reports · 2014Review
- Serrated pathway in colorectal carcinogenesis.World journal of gastroenterology · 2014Review
- Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management.Journal of gastroenterology · 2013Review
- A significant imbalance in mitosis versus apoptosis accelerates the growth rate of sessile serrated adenoma/polyps.Virchows Archiv : an international journal of pathology · 2013Article
- Article
- State of the Art Review: Colorectal Cancer Screening.American journal of lifestyle medicine · 2012Article
- Prognostic and predictive impact of DNA mismatch repair in the management of colorectal cancer.Future oncology (London, England) · 2011Article
- Serrated polyps of the colon.F1000 medicine reports · 2010Article
- Sessile serrated adenomas: demographic, endoscopic and pathological characteristics.World journal of gastroenterology · 2010Article
- Beta-catenin nuclear labeling is a common feature of sessile serrated adenomas and correlates with early neoplastic progression after BRAF activation.The American journal of surgical pathology · 2009Article
- Serrated adenomas.Current gastroenterology reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The fundamental view that colon adenocarcinomas arise only from conventional adenomas has been challenged by the now recognized hyperplastic polyp-serrated adenoma-adenocarcinoma pathway. This article describes the history of the serrated adenoma (both the traditional serrated adenoma and the sessile serrated adenoma) as well as the histology and endoscopic appearance of these lesions in comparison with hyperplastic polyps and mixed polyps. Although the exact pathway is the subject of ongoing research, compelling histologic associations and molecular phenotypes that define the model of the serrated polyp-carcinoma sequence, including microsatellite instability, BRAF/KRAS mutations, and CpG island methylator phenotype, provide strong evidence that this is a genuine pathway. Management of serrated neoplasia of the colon includes careful colonoscopy, complete removal of colonic polyps, sampling fields of diminutive polyps of the rectosigmoid, and basing surveillance on histology of removed polyps.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.