ReviewRadiation oncology (London, England)2008
Neuropsychological testing and biomarkers in the management of brain metastases.
Review in Radiation oncology (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Trial
- Effect of modulation factor and low dose threshold level on gamma pass rates of single isocenter multi-target SRT treatment plans.Journal of applied clinical medical physics · 2024Article
- ATR Inhibitor M6620 (VX-970) Enhances the Effect of Radiation in Non-Small Cell Lung Cancer Brain Metastasis Patient-Derived Xenografts.Molecular cancer therapeutics · 2021Article
- Development and characterization of patient-derived xenografts from non-small cell lung cancer brain metastases.Scientific reports · 2021Article
- Prospective memory and brain metastases: a relevant target for rehabilitation in post-operative patients?Journal of neuro-oncology · 2020Article
- Radiation Toxicity in the Central Nervous System: Mechanisms and Strategies for Injury Reduction.Seminars in radiation oncology · 2017Review
- Palliative Resection of Metastatic Brain Tumors Previously Treated by Stereotactic Radiosurgery.Brain tumor research and treatment · 2016Article
- Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis.Clinical & experimental metastasis · 2015Article
- [Diagnosis and therapy of cognitive deficits in oncology patients].Der Nervenarzt · 2015Article
- Impact of Grid Size on Dose Calculations for Cranial Tumors.Journal of medical physicsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Prognosis for patients with brain metastasis remains poor. Whole brain radiation therapy is the conventional treatment option; it can improve neurological symptoms, prevent and improve tumor associated neurocognitive decline, and prevents death from neurologic causes. In addition to whole brain radiation therapy, stereotactic radiosurgery, neurosurgery and chemotherapy also are used in the management of brain metastases. Radiosensitizers are now currently being investigated as potential treatment options. All of these treatment modalities carry a risk of central nervous system (CNS) toxicity that can lead to neurocognitive impairment in long term survivors. Neuropsychological testing and biomarkers are potential ways of measuring and better understanding CNS toxicity. These tools may help optimize current therapies and develop new treatments for these patients. This article will review the current management of brain metastases, summarize the data on the CNS effects associated with brain metastases and whole brain radiation therapy in these patients, discuss the use of neuropsychological tests as outcome measures in clinical trials evaluating treatments for brain metastases, and give an overview of the potential of biomarker development in brain metastases research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.