Evidence map›Paper›PMID 18797968›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2008

Integrating mouse anatomy and pathology ontologies into a phenotyping database: tools for data capture and training.

John P Sundberg, Beth A Sundberg, Paul Schofield

Open access · hybridAbstract read
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 43 citations in OpenAlex.

  1. Bridging mouse and human anatomies; a knowledge-based approach to comparative anatomy for disease model phenotyping.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Review
  2. Article
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  7. Mouse genome-wide association study identifies polymorphisms on chromosomes 4, 11, and 15 for age-related cardiac fibrosis.Mammalian genome : official journal of the International Mammalian Genome Society · 2016
    Article
  8. Article
  9. Article
  10. Genetic determinants of fibro-osseous lesions in aged inbred mice.Experimental and molecular pathology · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Retinoid metabolism is altered in human and mouse cicatricial alopecia.The Journal of investigative dermatology · 2013
    Article
  16. Training pathologists in mouse pathology.Veterinary pathology · 2012
    Article
  17. Whole-animal imaging, gene function, and the Zebrafish Phenome Project.Current opinion in genetics & development · 2011
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

John P SundbergThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609-1500, USA. john.sundberg@jax.org
Beth A Sundberg
Paul Schofield
Jackson Laboratory · USUniversity of Cambridge · GB

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Paul Robson · 1985 to 2026
$61.9M
Mouse Models of Human Cancer DatabaseR01CA089713 · NCI · JACKSON LABORATORY · PI BULT, CAROL J · 2002 to 2025
$17.5M
Shock Center for Aging Research at The Jackson Laborato*P30AG025707 · NIA · JACKSON LABORATORY · PI PAIGEN, BEVERLY J · 2005 to 2009
$4.1M
NCI NIH HHS CA089713NCI NIH HHS CA34196NCI NIH HHS P30 CA034196NCI NIH HHS R01 CA089713NIA NIH HHS AG025707NIA NIH HHS P30 AG025707
6 · The paper itself

Abstract

The Mouse Disease Information System (MoDIS) is a data capture system for pathology data from laboratory mice designed to support phenotyping studies. The system integrates the mouse anatomy (MA) and mouse pathology (MPATH) ontologies into a Microsoft Access database facilitating the coding of organ, tissue, and disease process to recognized semantic standards. Grading of disease severity provides scores for all lesions that can then be used for quantitative trait locus (QTL) analyses and haplotype association gene mapping. Direct linkage to the Pathbase online database provides reference definitions for disease terms and access to photomicrographic images of similar diagnoses in other mutant mice. MoDIS is an open source and freely available program (http://research.jax.org/faculty/sundberg/index.html). This provides a valuable tool for setting up a mouse pathology phenotyping program.

Indexed as

Databases, GeneticAnimalsDiseaseInformation SystemsMicePhenotype

Identifiers

PMID18797968
PMCPMC2844541
OpenAlexW2006917435

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.