ArticleDevelopment genes and evolution2008
C2H2 zinc finger genes of the Gli, Zic, KLF, SP, Wilms' tumour, Huckebein, Snail, Ovo, Spalt, Odd, Blimp-1, Fez and related gene families from Branchiostoma floridae.
Article in Development genes and evolution, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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25 citing papers in PubMed, 33 citations in OpenAlex.
- Evolutionary Dynamics and Functional Bifurcation of the C2H2 Gene Family in Basidiomycota.Journal of fungi (Basel, Switzerland) · 2025Article
- Single-cell Transcriptomic Studies Unveil Potential Nodes of the Notochord Gene Regulatory Network.Integrative and comparative biology · 2024Review
- Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories.Nature ecology & evolution · 2024Article
- AmphioxusMarine life science & technology · 2023Article
- Bioinformatics analysis of KLF2 as a potential prognostic factor in ccRCC and association with epithelial-mesenchymal transition.Experimental and therapeutic medicine · 2022Article
- PpZAT5 suppresses the expression of a B-box geneFrontiers in plant science · 2022Article
- Genome-Wide Identification and Expression Patterns of the C2H2-Zinc Finger Gene Family Related to Stress Responses and Catechins Accumulation inInternational journal of molecular sciences · 2021Article
- Krüppel-like factor/specificity protein evolution in the Spiralia and the implications for cephalopod visual system novelties.Proceedings. Biological sciences · 2020Article
- Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis.Molecular biology and evolution · 2020Article
- C2H2 Zinc Finger Proteins: Master Regulators of Abiotic Stress Responses in Plants.Frontiers in plant science · 2020Review
- Silencing of brain-expressed X-linked 2 (BEX2) promotes colorectal cancer metastasis through the Hedgehog signaling pathway.International journal of biological sciences · 2020Article
- Mutations inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Molecular regionalization of the developing amphioxus neural tube challenges major partitions of the vertebrate brain.PLoS biology · 2017Article
- Amphioxus Sp5 is a member of a conserved Specificity Protein complement and is modulated by Wnt/β-catenin signalling.The International journal of developmental biology · 2017Article
- Bilaterian-like promoters in the highly compact Amphimedon queenslandica genome.Scientific reports · 2016Article
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- KLF/SP Transcription Factor Family Evolution: Expansion, Diversification, and Innovation in Eukaryotes.Genome biology and evolution · 2015Article
- GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos.PloS one · 2013Article
- A new family of predicted Krüppel-like factor genes and pseudogenes in placental mammals.PloS one · 2013Article
- Ancient homeobox gene loss and the evolution of chordate brain and pharynx development: deductions from amphioxus gene expression.Proceedings. Biological sciences · 2010Article
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1 author at 1 institution in 1 country.
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Abstract
The C2H2 zinc finger is one of the most common domains encoded by animal genomes and has been implicated in DNA binding as well as protein-protein interactions and RNA binding. Genes encoding C2H2 zinc finger domains include not only well-studied conserved transcription factors such as Gli and Snail but also include a large diversity of more rapidly evolving genes. Here, I focus on the description of amphioxus members of families and super-families of C2H2 zinc finger genes that have been the subject of functional studies in other species, specifically the Gli, Zic, Glis, Snail, Scratch, Krox, Wilms' tumour, Huckebein, SP, KLF, Ovo, Spalt, Blimp-1, Odd and Fez genes. Surveys of the Branchiostoma floridae genome reveal members of all of these groups of genes. Genes are named according to molecular phylogenetic analyses, such that the nomenclature reflects pre-existing gene names in the context of gene families that have descended from a single common ancestral gene in the common ancestor of chordates and insects. In total, this comprises 28 B. floridae C2H2 zinc finger genes, representing at least 15 gene families. For 17 of these genes, expressed sequence tag clusters and associated clone identification codes relating to the B. floridae gene collection are given.
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