ArticleGenetica2009
Search for informative polymorphisms in candidate genes: clock genes and circadian behaviour in blue tits.
Article in Genetica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 51 citations in OpenAlex.
- Clinal Variation in Short Tandem Repeats Linked to Gene Expression in Sunflower (Biomolecules · 2024Article
- Birds of a feather flock together: a dataset for Clock and Adcyap1 genes from migration genetics studies.Scientific data · 2023Article
- Urbanization is associated with non-coding polymorphisms in candidate behavioural genes in the Eurasian coot.Ecology and evolution · 2023Article
- Clock-linked genes underlie seasonal migratory timing in a diurnal raptor.Proceedings. Biological sciences · 2022Article
- The genetic regulation of avian migration timing: combining candidate genes and quantitative genetic approaches in a long-distance migrant.Oecologia · 2021Article
- Shorebirds' Longer Migratory Distances Are Associated With LargerFrontiers in psychology · 2021Article
- Length polymorphisms at two candidate genes explain variation of migratory behaviors in blackpoll warblers (Ecology and evolution · 2019Article
- Life history shapes variation in egg composition in the blue titCommunications biology · 2019Article
- Examination of Clock and Adcyap1 gene variation in a neotropical migratory passerine.PloS one · 2018Article
- Clock gene is associated with individual variation in the activation of reproductive endocrine and behavior of Asian short toed lark.Scientific reports · 2017Article
- Candidate genes have sex-specific effects on timing of spring migration and moult speed in a long-distance migratory bird.Current zoology · 2017Article
- Adcyap1 polymorphism covaries with breeding latitude in a Nearctic migratory songbird, the Wilson's warbler (Cardellina pusilla).Ecology and evolution · 2016Article
- Candidate gene-environment interactions and their relationships with timing of breeding in a wild bird population.Ecology and evolution · 2015Article
- Influence of ecological and geological features on rangewide patterns of genetic structure in a widespread passerine.Heredity · 2015Article
- Interactions between a Candidate Gene for Migration (ADCYAP1), Morphology and Sex Predict Spring Arrival in Blackcap Populations.PloS one · 2015Article
- No Association between Personality and Candidate Gene Polymorphisms in a Wild Bird Population.PloS one · 2015Article
- Parental care, loss of paternity and circulating levels of testosterone and corticosterone in a socially monogamous song bird.Frontiers in zoology · 2014Article
- Variation in candidate genes CLOCK and ADCYAP1 does not consistently predict differences in migratory behavior in the songbird genus Junco.F1000Research · 2013Article
- Testing for associations between candidate genes for circadian rhythms and individual variation in sleep behaviour in blue tits.Genetica · 2012Article
- Identification of a gene associated with avian migratory behaviour.Proceedings. Biological sciences · 2011Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification of functional polymorphisms in genes that underlie behavioural trait variation is a challenging but intriguing task in evolutionary biology. Given the wealth of genomic data and the increasing number of genotype-phenotype association studies in model organisms, one can ask whether and how this information can be used for non-model organisms. Here we describe two strategies to search for likely functional polymorphisms in candidate genes in a bird species that has been intensively studied by behavioural and population ecologists, the blue tit Cyanistes caeruleus. In the first approach we searched for repeating elements in coding regions of the genome using information about repeats in Gallus gallus genes. The rationale is that tandem-repeat elements have a high potential to be polymorphic and functional. The second strategy aimed to replicate reported genotype-phenotype association studies by extrapolating results from model organisms to our study species. Both strategies showed high success rates with respect to finding homologous gene regions and potentially informative genetic variants in the genes AANAT, ADCYAP1, CKIepsilon, CLOCK, CREB1, NPAS2 and PERIOD2.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.