ReviewIntensive care medicine2008
Renal replacement therapies: physiological review.
Review in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Validation of a Simple-to-use Nomogram for Predicting In-hospital Mortality in Acute Heart Failure Patients Undergoing Continuous Renal Replacement Therapy
Comparison Between the Effect of Continuous Renal Replacement Therapy Versus Plasmapheresis on Mortality Rate in Aluminum Phosphide Poisoning; Randomized Controlled Study
Who cites it
17 citing papers in PubMed, 49 citations in OpenAlex.
- Regional citrate anticoagulation for pediatric CRRT using integrated citrate software and physiological sodium concentration solutions.Pediatric nephrology (Berlin, Germany) · 2014Trial
- Obesity and mortality in KDIGO stage 3 acute kidney injury: a machine learning-driven retrospective cohort study.BMC nephrology · 2025Article
- Saline flushing to prevent circuit clotting during CRRT without anticoagulant: a randomized controlled study.BMC nursing · 2025Article
- Perforated colon cancer complicated by necrotizing soft tissue infection: A case report and literature review.IDCases · 2025Article
- Machine learning prediction models for mortality risk in sepsis-associated acute kidney injury: evaluating early versus late CRRT initiation.Frontiers in medicine · 2024Article
- Development and Validation of a Simple-to-Use Nomogram for Predicting In-Hospital Mortality in Patients With Acute Heart Failure Undergoing Continuous Renal Replacement Therapy.Frontiers in medicine · 2021Article
- Prescription of CRRT: a pathway to optimize therapy.Annals of intensive care · 2020Review
- Ultrasound-based clinical profiles for predicting the risk of intradialytic hypotension in critically ill patients on intermittent dialysis: a prospective observational study.Critical care (London, England) · 2019Observational
- Echocardiographic parameters of patients in the intensive care unit undergoing continuous renal replacement therapy.PloS one · 2019Article
- Observational
- Renal Replacement Therapy.F1000Research · 2016Review
- The implications and management of septic acute kidney injury.Nature reviews. Nephrology · 2011Review
- Clinical review: Optimal dose of continuous renal replacement therapy in acute kidney injury.Critical care (London, England) · 2011Review
- High rate ultrafiltration in anasarca: 33 l of net negative fluid balance in 52 h!Intensive care medicine · 2011Article
- Management of metformin-associated lactic acidosis by continuous renal replacement therapy.PloS one · 2011Article
- Controversies in acute kidney injury: the 2011 Brussels Roundtable.Critical care (London, England) · 2011Article
- Year in review in Intensive Care Medicine, 2008: I. Brain injury and neurology, renal failure and endocrinology, metabolism and nutrition, sepsis, infections and pneumonia.Intensive care medicine · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionA physiological review on renal replacement therapies (RRT) is a challenging task: there is nothing "physiologic" about RRT, since the most accurate, safe and perfectly delivered extracorporeal therapy would still be far from "physiologically" replacing the function of the native kidney.
methodsThis review will address the issues of physiology of fluid and solute removal, acid base control and impact on mortality during intermittent and continuous therapies: different RRT modalities and relative prescriptions will provide different "physiological clinical effects" to critically ill patients with acute kidney injury (AKI), with the aim of restoring lost "renal homeostasis". On the other side, however, the "pathophysiology" of RRT, consists with unwanted clinical effects caused by the same treatments, generally under-recognized by current literature but often encountered in clinical practice. Physiology and pathophysiology of different RRT modalities have been reviewed.
conclusionPhysiology and pathophysiology of RRT often coexist during dialysis sessions. Improvement in renal recovery and survival from AKI will be achieved from optimization of therapy and increased awareness of potential benefits and dangers deriving from different RRT modalities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.