ArticleGenetics2008
The genetic architecture of complex traits in teosinte (Zea mays ssp. parviglumis): new evidence from association mapping.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 77 citations in OpenAlex.
- Identification of superior haplotypes for flowering time in pigeonpea through candidate gene-based association study of a diverse minicore collection.Plant cell reports · 2024Article
- A Novel RHS1 Locus in Rice Attributes Seed-Pod Shattering by the Regulation of Endogenous S-Nitrosothiols.International journal of molecular sciences · 2022Article
- The Past, Present, and Future of Maize Improvement: Domestication, Genomics, and Functional Genomic Routes toward Crop Enhancement.Plant communications · 2020Review
- Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude.PLoS genetics · 2019Article
- Development and evaluation of high-density AxiomPlant biotechnology journal · 2018Article
- Defining the Role of the MADS-Box Gene, Zea Agamous-like1, a Target of Selection During Maize Domestication.The Journal of heredity · 2018Article
- Domestication as a model system for the extended evolutionary synthesis.Interface focus · 2017Review
- Quantitative trait loci from identification to exploitation for crop improvement.Plant cell reports · 2017Review
- Deciphering the genetic control of fruit texture in apple by multiple family-based analysis and genome-wide association.Journal of experimental botany · 2017Article
- Origin of rice (Genetic resources and crop evolution · 2017Article
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- Review
- Locally epistatic genomic relationship matrices for genomic association and prediction.Genetics · 2015Article
- Article
- Entering the second century of maize quantitative genetics.Heredity · 2014Review
- Evolution of crop species: genetics of domestication and diversification.Nature reviews. Genetics · 2013Review
- The promise of genomics in the study of plant-pollinator interactions.Genome biology · 2013Review
- Article
- Complex patterns of local adaptation in teosinte.Genome biology and evolution · 2013Article
- Diversity in global maize germplasm: characterization and utilization.Journal of biosciences · 2012Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
Previous association analyses showed that variation at major regulatory genes contributes to standing variation for complex traits in Balsas teosinte, the progenitor of maize. This study expands our previous association mapping effort in teosinte by testing 123 markers in 52 candidate genes for association with 31 traits in a population of 817 individuals. Thirty-three significant associations for markers from 15 candidate genes and 10 traits survive correction for multiple testing. Our analyses suggest several new putative causative relationships between specific genes and trait variation in teosinte. For example, two ramosa genes (ra1 and ra2) associate with ear structure, and the MADS-box gene, zagl1, associates with ear shattering. Since zagl1 was previously shown to be a target of selection during maize domestication, we suggest that this gene was under selection for its effect on the loss of ear shattering, a key domestication trait. All observed effects were relatively small in terms of the percentage of phenotypic variation explained (<10%). We also detected several epistatic interactions between markers in the same gene that associate with the same trait. Candidate-gene-based association mapping appears to be a promising method for investigating the inheritance of complex traits in teosinte.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.