ArticleThe Journal of allergy and clinical immunology2008
Increased risk of serious pneumococcal disease in patients with asthma.
Article in The Journal of allergy and clinical immunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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Who cites it
89 citing papers in PubMed, 159 citations in OpenAlex.
- Atopic conditions other than asthma and risk of the 2009 novel H1N1 infection in children: a case-control study.Allergy and asthma proceedingsTrial
- Application of a natural language processing algorithm to early asthma ascertainment for adults in the era of electronic health records.The journal of allergy and clinical immunology. Global · 2026Article
- Artificial intelligence biomarker detects high-risk childhood asthma subgroup for respiratory infections and exacerbations.The Journal of allergy and clinical immunology · 2025Article
- Predictive model and prognostic insights into duodenal stump fistula following radical gastrectomy with Roux-en-Y reconstruction for gastric cancer.World journal of gastrointestinal surgery · 2025Article
- Coverage of Recommended Vaccination Among Adult Patients With Asthma in Riyadh, Saudi Arabia.Cureus · 2024Article
- A systematic review and meta-analysis of the correlation between cough variant asthma and mycoplasma pneumonia in children.Archives of medical science : AMS · 2024Review
- Asthma and Respiratory Infections From Birth to Young Adulthood.American journal of epidemiology · 2023Article
- A comprehensive overview of pneumococcal vaccination recommendations for adults in South Africa, 2022.Journal of thoracic disease · 2022Review
- Risk Factors of Pneumonia in Primary Antibody Deficiency Patients Receiving Immunoglobulin Therapy: Data from the US Immunodeficiency Network (USIDNET).Journal of clinical immunology · 2022Article
- Atopic asthma as a potentially significant but unrecognized risk factor for Kawasaki disease in children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022Article
- Trained immunity in type 2 immune responses.Mucosal immunology · 2022Review
- Article
- House Dust Mite Aeroallergen Suppresses Leukocyte Phagocytosis and Netosis Initiated by Pneumococcal Lung Infection.Frontiers in pharmacology · 2022Article
- Risk of Pleural Empyema in Adult Patients With Asthma: A Nationwide Retrospective Cohort Study.Frontiers in medicine · 2022Article
- Establishing an expert consensus for the operational definitions of asthma-associated infectious and inflammatory multimorbidities for computational algorithms through a modified Delphi technique.BMC medical informatics and decision making · 2021Article
- Risk, Mechanisms and Implications of Asthma-Associated Infectious and Inflammatory Multimorbidities (AIMs) among Individuals With Asthma: a Systematic Review and a Case Study.Allergy, asthma & immunology research · 2021Review
- Factors associated with IgG levels in adults with IgG subclass deficiency.BMC immunology · 2021Article
- A diagnostic codes-based algorithm improves accuracy for identification of childhood asthma in archival data sets.The Journal of asthma : official journal of the Association for the Care of Asthma · 2021Article
- Respiratory tract infections in children with allergic asthma on allergen immunotherapy during influenza season.Scientific reports · 2021Article
- Association between asthma and invasive pneumococcal disease risk: a systematic review and meta-analysis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2020Review
29 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundIndividuals with asthma have been reported to be at increased risk of invasive pneumococcal disease (IPD). These findings need to be confirmed in a different population-based study setting.
objectiveWe assessed whether serious pneumococcal disease (SPD), defined as an IPD, pneumococcal pneumonia, or both, was associated with asthma status.
methodsThis is a retrospective case-control study using criteria-based methods for ascertaining SPD, as well as asthma. Subjects were residents of Rochester, Minnesota, who had SPD between 1964 and 1983 (the primarily pre-pneumococcal vaccine era) and their age- and sex-matched control subjects using 1:2 matching. Potential cases and control subjects were identified by using the Rochester Epidemiology project database and confirmed by medical record reviews. All cases and control subjects were merged with the database comprising the entire pool of Rochester residents with and without asthma between 1964 and 1983.
resultsA total of 3941 records of potential patients with SPD were reviewed, and we identified 174 cases of SPD (51% male subjects and 94% white subjects). SPD was associated with a history of asthma among all ages (odds ratio, 2.4; 95% CI, 0.9-6.6; P = .09) and among adults (odds ratio, 6.7; 95% CI, 1.6-27.3; P = .01), controlling for high-risk conditions for IPD and smoking exposure. The population-attributable risk percentage was 17% in the adult population.
conclusionAdults with asthma might be at increased risk of SPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.