Evidence map›Paper›PMID 18790389›Full record

ReviewTrends in cardiovascular medicine2008

Novel biomarkers for predicting preeclampsia.

David M Carty, Christian Delles, Anna F Dominiczak

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in cardiovascular medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 161 citations in OpenAlex.

  1. Clinical, Laboratory and Radiological Factors associated with posterior reversible encephalopathy syndrome (PRES) in patients with eclampsia or pre-eclampsia: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. T174M-M235TCurrent issues in molecular biology · 2026
    Article
  6. Late vs. Early Preeclampsia.International journal of molecular sciences · 2025
    Review
  7. Observational
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. 4-Hydroxyglutamate is a novel predictor of pre-eclampsia.International journal of epidemiology · 2020
    Article
  18. Role of soluble endoglin in BMP9 signaling.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  19. The potential role of pregnancy-associated plasma protein-A2 in angiogenesis and development of preeclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David M CartyBHF Glasgow Cardiovascular Research Centre, University of Glasgow, G12 8TA Glasgow, United Kingdom.
Christian Delles
Anna F Dominiczak
University of Glasgow · GB

Funding

British Heart Foundation RG/07/005/23633
6 · The paper itself

Abstract

Preeclampsia is a major cause of maternal morbidity and mortality worldwide. Despite decades of research into the condition, the ability of clinicians to predict preeclampsia prior to the onset of symptoms has not improved significantly. In this review, we will examine the pathophysiology underlying preeclampsia and will look at potential biomarkers for early prediction and diagnosis. In addition, we will explore potential future areas of research into the condition.

Indexed as

ActivinsAngiogenesis Inducing AgentsAntigens, CDApolipoproteins EBiomarkersEndoglinFemaleHumansInhibinsInsulin ResistancePre-EclampsiaPregnancyPregnancy-Associated Plasma Protein-AReceptors, Cell SurfaceVascular Endothelial Growth Factor Receptor-1activin AActivinsAngiogenesis Inducing AgentsAntigens, CDApolipoproteins EBiomarkersEndoglinENG protein, humanFLT1 protein, humaninhibin AInhibinsPAPPA2 protein, humanPregnancy-Associated Plasma Protein-AReceptors, Cell SurfaceVascular Endothelial Growth Factor Receptor-1

Identifiers

PMID18790389
PMCPMC2577131
OpenAlexW2011916431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.