Evidence map›Paper›PMID 18788826›Full record

ArticleNano letters2008

Resolving sub-diffraction limit encounters in nanoparticle tracking using live cell plasmon coupling microscopy.

Guoxin Rong, Hongyun Wang, Lynell R Skewis, Björn M Reinhard

Abstract read
In one paragraph

Article in Nano letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Guoxin RongDepartment of Chemistry and The Photonics Center, Boston University, Boston, Massachusetts 02215, USA.
Hongyun Wang
Lynell R Skewis
Björn M Reinhard

Funding

Illuminating Dynamic Receptor Clustering in the Epidermal Growth Factor Receptor Signal Transduction Pathway Using Plasmon CouplingR01CA138509 · NCI · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Bjoern Markus Reinhard · 2009 to 2026
$5.9M
Plasmon Coupling Microscopy for the in vivo Detection and Tracking of CytoplasmicR21EB008822 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI REINHARD, BJOERN MARKUS · 2008 to 2009
$431k
NCI NIH HHS N01 CM062209NCI NIH HHS R01 CA138509NIBIB NIH HHS 1 R21 EB008822-01NIBIB NIH HHS R21 EB008822
6 · The paper itself

Abstract

We use plasmon coupling between individual gold nanoparticle labels to monitor subdiffraction limit distances in live cell nanoparticle tracking experiments. While the resolving power of our optical microscope is limited to approximately 500 nm, we improve this by more than an order of magnitude by detecting plasmon coupling between individual gold nanoparticle labels using a ratiometric detection scheme. We apply this plasmon coupling microscopy to resolve the interparticle separations during individual encounters of gold nanoparticle labeled fibronectin-integrin complexes in living HeLa cells.

Indexed as

Cell MembraneFibronectinsGoldHeLa CellsHumansIntegrinsMetal NanoparticlesMicroscopyNanoparticlesNanotechnologyOptics and PhotonicsSurface Plasmon ResonanceFibronectinsGoldIntegrins

Identifiers

PMID18788826
PMCPMC2684112

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.