ArticleHistochemistry and cell biology2009
P2X receptors are differentially expressed on vasopressin- and oxytocin-containing neurons in the supraoptic and paraventricular nuclei of rat hypothalamus.
Article in Histochemistry and cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Cell Type-Specific Expression of Purinergic P2X Receptors in the Hypothalamus.International journal of molecular sciences · 2025Review
- Oxytocin treatment rescues irritability-like behavior in Cc2d1a conditional knockout mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- On P2X receptors in the brain: microvessels. Dedicated to the memory of the late Professor Geoffrey Burnstock (1929-2020).Cell and tissue research · 2021Review
- Ion Channels in the Paraventricular Hypothalamic Nucleus (PVN); Emerging Diversity and Functional Roles.Frontiers in physiology · 2018Review
- Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus.Cell and tissue research · 2017Article
- Purinergic signaling pathways in endocrine system.Autonomic neuroscience : basic & clinical · 2015Review
- ATP stimulates rat hypothalamic sympathetic neurons by enhancing AMPA receptor-mediated currents.Journal of neurophysiology · 2015Article
- Purinergic signalling in endocrine organs.Purinergic signalling · 2014Review
- Purinergic and glutamatergic interactions in the hypothalamic paraventricular nucleus modulate sympathetic outflow.Purinergic signalling · 2013Article
- Developmental expression of P2X5 receptors in the mouse prenatal central and peripheral nervous systems.Purinergic signalling · 2013Article
- Potentiation of inhibitory synaptic transmission by extracellular ATP in rat suprachiasmatic nuclei.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.Molecular neurobiology · 2012Review
- Regional expression of P2Y(4) receptors in the rat central nervous system.Purinergic signalling · 2011Article
- Bench-to-bedside review: Vasopressin in the management of septic shock.Critical care (London, England) · 2011Review
- Extending the knowledge in histochemistry and cell biology.Histochemistry and cell biology · 2010Review
- Purinergic regulation of hypothalamopituitary functions.Trends in endocrinology and metabolism: TEM · 2009Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, the distribution of P2X receptor protein and colocalization of P2X receptors with vasopressin and oxytocin in the supraoptic and paraventricular nuclei of rat hypothalamus was studied using double-labeling fluorescence immunohistochemistry. The results showed that vasopressin-containing neurons expressed P2X(2), P2X(4), P2X(5) and P2X(6) receptor and oxytocin-containing neurons expressed P2X(2), P2X(4) and P2X(5) receptors in the supraoptic nucleus. In the paraventricular nucleus, vasopressin-containing neurons expressed P2X(4), P2X(5) and P2X(6) receptors, while oxytocin-containing neurons expressed P2X(4) receptors. This study provides the first evidence that P2X receptor subunits are differentially expressed on vasopressin- and oxytocin-containing neurons in the supraoptic and paraventricular nuclei, and hence, provides a substantial neuroanatomical basis for possible functional interactions between the purinergic and vasopressinergic systems, and the purinergic and oxytocinergic systems in the rat hypothalamus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.